Do you really need to inject HCG twice a week?

[Cataceous]

Dr Saya showed that 500 IU HCG only stays in your system for around 72 hours. 150 IU lasted 1 day.

The problem with this study is that the results are right at the limit of detectability—1 mIU/mL. If you take the 500 IU data and divide it by 3.333 (500/150), then add a little noise, the result is still consistent with the 150 IU data. I don't think the conclusion of a shorter duration for a smaller dose is justified by this alone.

 

[Nelson Vergel]

The problem with this study is that the results are right at the limit of detectability—1 mIU/mL. If you take the 500 IU data and divide it by 3.333 (500/150), then add a little noise, the result is still consistent with the 150 IU data. I don't think the conclusion of a shorter duration for a smaller dose is justified by this alone.

Good point. Do your testicles remain full at 150 IU of HCG per day?

In the case of HCG (in my opinion), the peak is as important as the area under the curve.

 

[Vince Carter]

Vince is your hcg from empower?

Yes

 

[Cataceous]

Good point. Do your testicles remain full at 150 IU of HCG per day?
...

I've tried 100 IU qd, 300 IU qod and 250 IU qod and cannot say I noticed a difference.

 

[Nelson Vergel]

I've tried 100 IU qd, 300 IU qod and 250 IU qod and cannot say I noticed a difference.

None of those doses have made any difference for me either. 500 IU twice per week is effective for me (for testicular fullness)

 

[joshmaximus]

None of those doses have made any difference for me either. 500 IU twice per week is effective for me (for testicular fullness)

Nelson do u get empower hcg? I like it better than aps pharmacy but it's probably all in my head..lol.

 

[Nelson Vergel]

Yes. I use this one ( two 6,000 IU at a time)
HCG Injections - Fact Sheet: Interactions, Side Effects, & Storage

 

[Cataceous]

None of those doses have made any difference for me either. 500 IU twice per week is effective for me (for testicular fullness)

I should have been clearer: All three doses have seemed adequate for reducing testicular atrophy. But I haven't tried the 17 - OH Progesterone test. Have you?

 

[Nelson Vergel]

I should have been clearer: All three doses have seemed adequate for reducing testicular atrophy. But I haven't tried the 17 - OH Progesterone test. Have you?

No. That test is for men who do not want to wait for 8 weeks to see if their semen has normalized on TRT + HCG. Doses under 500 IU three times per week usually don't work for that purpose.

 

[Cataceous]

No. That test is for men who do not want to wait for 8 weeks to see if their semen has normalized on TRT + HCG. Doses under 500 IU three times per week usually don't work for that purpose.

I wonder why that is? I see there is sort of a low-dose cutoff, but it's supposed to be somewhere under 250 IU hCG qod. This study on the correlation suggests that ~250 IU hCG qod restores ITT close to normal and 500 IU actually increases ITT significantly above normal. The 17 - OH Progesterone numbers reflect this, although not at the lower hCG dose of 125 IU qod.