rhino5169 - Have you taken DHEA before? If not, I'd suggest starting at a considerably lower dose for a few days and see how you respond to it. I was feeling pretty good, but noticed my DHEA labs were low, so I bought ultra micronized DHEA from DHEA.com. Took 25mg one night and felt like garbage the next day. Eventually I got a little relief when cutting my dose down to 12mg. And yet more relief when dropping it to 6mg, before finally feeling much better just days after discontinuing it. I feel much better without it. We're all different, maybe it will help you feel better, just start with a lower dose and be patient (increase dose as symptoms and labs warrant). Sound advice IMO with most anything HRT related. Good luck.