DHEA Interesting Results

[Leesto]

Note: This information is anecdotal and from one person only. I'm not recommending or suggesting anything - just sharing what happened to me.

Six months ago Defy recommended that I try DHEA supplementation at 25 Mg/day for low libido. Libido didn't change but three things did!

1) I changed from a "grower" to a "shower". My soft penis had always been about 1" long. All shriveled up. Within 2 days it changed to around 4" long and has remained that way ever since.

2) I had not had a nocturnal erection for more than 2 decades. Two days after starting DHEA I began having quite strong and regular nocturnal erections. Now I have them 5 or 6 days a week.

3) Prior to this I had not been able to get an erection without trimix. Even 4 100 mg. viagras did not work. Lots of side effects but no erections. Within a few weeks of starting DHEA supplementation I was able to get erections with no viagra but not reliably. Over the next few months this improved. I quit trimix because six months later I can now probably get an erection on demand but if I want to be sure I take two viagras.

Protocol:

.5 ml. T-Cyp 200 2X/week.
400 IU HCG 2X/week
Daily Cialis 5 mg.
Daily DHEA 25 mg
Daily Multivitamin
Daily Baby Aspirin
Metformin 1000 mg. 2X Daily
Note: I do not use an AI.

Recent Labs:

Total T: 1143 (264-916)
Free T: 33.6 (6.6-18.1)
Estradiol (sensitive): 29.1 (8.0-35.0)
DHEA - Sulfate: 542.6 (48.9-344.2)
SHBG: 25.2 (19.3-78.4)
Hematocrit: 47.9

I did not expect any of these changes to happen but as you can imagine I am happy about them as is my wife.

Leesto

 

[Vince Carter]

By all means this is good news. Side question...how are you doing with HCT which I see is good but more curious to having your Free T twice the lab range (2.9%). SHBG and E2 look in close proximity to each other which I think is good.

 

[Renman23]

The Dr. just prescribed DHEA for me (50mg daily). I'm looking forward to seeing how it helps...
I'll be starting my protocall next week...

But thanks for posting and hope your results are long term!

 

[Vince]

Be careful when supplementing with DHEA, I supplement only to keep my DHEA levels in a good range. In men DHEA will increase your estradiol levels and lower your testosterone levels.

I take 25 mg of DHEA before bed, it actually helps me get a good night sleep.

 

[ratbag]

I see that you have relatively low SHBG. This makes me wonder if your protocol could be improved by dosing daily or EOD. Twice a week may be pushing it with your SHBG level.

 

[Vince Carter]

50mg/D is way too much DHEA. Try 5-10mg...know that DHEA can aromatase extremely easily, depending on how you take it. An oral micronized version or trasndermal is better but do NOT take the cheap tablets you can find at walmart et al..,

 

[Leesto]

I see that you have relatively low SHBG. This makes me wonder if your protocol could be improved by dosing daily or EOD. Twice a week may be pushing it with your SHBG level.

Honestly I don't know the answer to that. I am doing pretty darn well on the current protocol so hate to tinker with it unless I get symptoms that need to be addressed. Will keep this in mind though!

 

[Leesto]

By all means this is good news. Side question...how are you doing with HCT which I see is good but more curious to having your Free T twice the lab range (2.9%). SHBG and E2 look in close proximity to each other which I think is good.

Vince HCT seems to stay around 48. I don't need phlebotomy or blood donations. Lucky I guess! I feel good on this protocol and in my recent consult they didn't say anything about the Free T so I assume they aren't concerned about it. I don't know the side effects or dangers of high Free T so it doesn't concern me either. Maybe it should?

Leesto

 

[Renman23]

https://www.amazon.com/dp/B004I229X..._rd_r=KBWJTKX1T7Y6PAACZ86R&pd_rd_w=tSOhL&th=1

Anyone familiar with this brand?

 

[Vince Carter]

Given you're not having the sides typically associated with Free T levels being too high...then all is well.

 

[Leesto]

Be careful when supplementing with DHEA, I supplement only to keep my DHEA levels in a good range. In men DHEA will increase your estradiol levels and lower your testosterone levels.

I take 25 mg of DHEA before bed, it actually helps me get a good night sleep.

Thanks Vince. I take 25 mg of DHEA before bed too and I sleep like a log. I'm in bed before 10 pm and I pop up refreshed every day at 5:30 am.

Thanks for the info about DHEA as it relates to estradiol and testosterone. Did not know that. So far so good but I'll remember that for future reference.

Leesto

 

[Vince]

https://www.amazon.com/dp/B004I229X..._rd_r=KBWJTKX1T7Y6PAACZ86R&pd_rd_w=tSOhL&th=1

Anyone familiar with this brand?

Life extension, I definitely would consider that a good brand. In the past I use Pure brand, I switch to Jarrow and I actually like it better plus it's a lower cost.

 

[Renman23]

Life extension, I definitely would consider that a good brand. In the past I use Pure brand, I switch to Jarrow and I actually like it better plus it's a lower cost.

Thanks Vince.

 

[ratbag]

Honestly I don't know the answer to that. I am doing pretty darn well on the current protocol so hate to tinker with it unless I get symptoms that need to be addressed. Will keep this in mind though!

This is a good answer. I wasn't sure how you felt. Glad you are feeling good.

 

[vibnad]

Hi guys, how long would it take dhea to raise estradiol. I have low dhea-s and estogen compared to my tesosterone. Have you actually seen bloodwork showing estradiol increasing after dhea supplementation?

 

[Vince]

Hi guys, how long would it take dhea to raise estradiol. I have low dhea-s and estogen compared to my tesosterone. Have you actually seen bloodwork showing estradiol increasing after dhea supplementation?

Yes I have seen my estradiol levels increase as I increase my DHEA. It does convert testosterone into estrogen, how long does it take. I've always waited at least 12 weeks to have Labs after changing my protocol.

 

[Powerdome]

Be careful when supplementing with DHEA, I supplement only to keep my DHEA levels in a good range. In men DHEA will increase your estradiol levels and lower your testosterone levels.

I take 25 mg of DHEA before bed, it actually helps me get a good night sleep.

For guys that have E2 issues, one of the docs frequently on the TRT podcast recommends 7-Keto DHEA to combat that problem

 

[MarkM]

I have never heard of 7 Keto DHEA controlling or helping with E2 issues. 7 Keto DHEA is actually a DHEA metabolite and cannot convert back into DHEA in the body. It is not converted to testosterone or estrogens, but it does has beneficial properties of its own, such as increasing metabolism by thermogenesis (fat burning) activity. It is several times more potent than DHEA in stimulating the thermogenic enzymes of the liver, promotes basal metabolism, and helps to increase the lean/adipose ratio. I take it daily to help in staying lean.

 

[Jayway25]

Note: This information is anecdotal and from one person only. I'm not recommending or suggesting anything - just sharing what happened to me.

Six months ago Defy recommended that I try DHEA supplementation at 25 Mg/day for low libido. Libido didn't change but three things did!

1) I changed from a "grower" to a "shower". My soft penis had always been about 1" long. All shriveled up. Within 2 days it changed to around 4" long and has remained that way ever since.

2) I had not had a nocturnal erection for more than 2 decades. Two days after starting DHEA I began having quite strong and regular nocturnal erections. Now I have them 5 or 6 days a week.

3) Prior to this I had not been able to get an erection without trimix. Even 4 100 mg. viagras did not work. Lots of side effects but no erections. Within a few weeks of starting DHEA supplementation I was able to get erections with no viagra but not reliably. Over the next few months this improved. I quit trimix because six months later I can now probably get an erection on demand but if I want to be sure I take two viagras.

Protocol:

.5 ml. T-Cyp 200 2X/week.
400 IU HCG 2X/week
Daily Cialis 5 mg.
Daily DHEA 25 mg
Daily Multivitamin
Daily Baby Aspirin
Metformin 1000 mg. 2X Daily
Note: I do not use an AI.

Recent Labs:

Total T: 1143 (264-916)
Free T: 33.6 (6.6-18.1)
Estradiol (sensitive): 29.1 (8.0-35.0)
DHEA - Sulfate: 542.6 (48.9-344.2)
SHBG: 25.2 (19.3-78.4)
Hematocrit: 47.9

I did not expect any of these changes to happen but as you can imagine I am happy about them as is my wife.

Leesto

Did supplementing with the DHEA continue to keep E2 levels up? I'm having a hard time keeping my E2 levels up.