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Hi All,

I've been on clomid for a few months and have been noticing some changes in my sex drive and libido. I got on clomid purely to boost my testosterone for mild anabologic effects. My T was already pretty strong at 750 ng/dl. Dr. Saya put me on clomid, 12.5mg per day, and my levels essentially doubled to 1470 ng/dl, and my estradiol shot up to 75 pg/ml. He decided to reduce my clomid to 3x per week and added anastrozole (.25mg per week) to reduce my estradiol. A few weeks later, my T came down to 1,120 and my estradiol to 38.

Once I started the anastrozole, though, I started to notice a sharp reduction in my libido/sex drive. My understanding was that high estrogen levels have that effect, so it's strange that I only started to experience it once the levels came down. This got me concerned, so I got off them altogether. I noticed a week of improvement, then a decline again.

I had the following questions:
1. Would you all recommend that I get off the clomid and anastrozole due to these effects, or is it normal for there to be these changes while you're finding the right balance between testosterone and estrogen?
2. Are these changes to my libido (and tangentially to my erectile health) possibly permanent? I'm always paranoid of having messed myself up for good, so if someone could explain whether my fears are warranted or if everything is likely to go back to normal once I fix everything, that would be appreciated.

Thank you all for your help. Attaching my lab results in case it assists.

@Simbarn
You may try DIM, it is not as strong as Anastrozole. Also calcium d-glucarate works too, I feel DIM more myself when I use it. The short of it is, they are involved in estrogen metabolism and excrete estrogen instead of it being cycled back through the body.
 
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