Blood Levels of Trace Elements and Testosterone

Nelson Vergel

Founder, ExcelMale.com
Very good read about elements that were associated with lower and higher testosterone blood levels

Background/Objectives: Modern societal stressors have been linked to declining testosterone levels among young men, contributing to somatic, psychological, and sexual health problems. Despite growing evidence suggesting a link between trace elements and testosterone-related symptoms, there are only a few comprehensive analyses on younger populations. This study’s aim was to examine how serum trace elements modulate the relationship between testosterone levels and symptom severity. Methods: This cross-sectional study included 225 young men seeking infertility consultation in Japan. Serum total and free testosterone levels were measured, along with self-reported symptoms using the Aging Males’ Symptoms scale (somatic, psychological, sexual) and the Erection Hardness Score. The serum concentrations of 20 trace elements were measured. We used unsupervised clustering to classify participants based on testosterone levels and symptom severity and then compared the distribution of trace elements among the resulting clusters. Results: Three distinct clusters emerged: (1) lowest testosterone with highest symptom severity, (2) intermediate, and (3) highest testosterone with minimal symptoms. Interestingly, the intermediate cluster displayed low testosterone levels but minimal symptoms. Eleven trace elements (phosphorus, sulfur, potassium, calcium, iron, zinc, arsenic, rubidium, strontium, molybdenum, and cesium) were identified as potential contributors to testosterone dynamics. Weighted quantile sum regression indicated that phosphorus, strontium, and molybdenum negatively influenced testosterone outcomes, whereas iron, sulfur, and zinc were beneficial. Conclusions: Serum trace element profiles are significantly associated with testosterone levels and symptom severity in young men. Targeted interventions may address testosterone decline and its implications. These findings may help develop tailored strategies for optimizing male health.

 
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Below is an overview of foods that are naturally rich in iron, sulfur, and zinc. Including these in your diet can help you maintain adequate levels of these key nutrients. If you suspect a deficiency or want to track your nutrient status, consider getting a blood test to measure these levels.


Iron-Rich Foods​

  1. Red Meat (beef, lamb, venison): Known for high bioavailable iron (heme iron).
  2. Organ Meats (liver, kidney): Extremely iron-dense and also high in other nutrients like vitamin B12.
  3. Legumes (lentils, chickpeas, beans): Provide non-heme iron; pairing them with vitamin C–rich foods (e.g., bell peppers) can improve iron absorption.
  4. Dark Leafy Greens (spinach, kale): Offer non-heme iron; combine with citrus fruits or tomatoes to boost absorption.
  5. Fortified Cereals: Many breakfast cereals are fortified with iron, a practical option for plant-based eaters.

Sulfur-Rich Foods​

  1. Allium Vegetables (onions, garlic, shallots): High in sulfur compounds believed to support antioxidant activity.
  2. Cruciferous Vegetables (broccoli, cabbage, cauliflower, Brussels sprouts): Contain sulfur-rich glucosinolates, linked to various health benefits.
  3. Eggs: Yolks contain sulfur-based amino acids, which also aid in healthy hair and nails.
  4. Protein Sources (meat, poultry, fish): Animal proteins generally provide sulfur-containing amino acids like methionine and cysteine.

Zinc-Rich Foods​

  1. Shellfish (oysters, crab, lobster): Oysters, in particular, are famously high in zinc.
  2. Red Meat and Poultry: Common sources of zinc with good bioavailability.
  3. Pumpkin Seeds: Plant-based zinc option; also provide healthy fats and antioxidants.
  4. Nuts (cashews, almonds): Great for light snacking and adding extra zinc to your diet.
  5. Whole Grains (oats, quinoa): Contain zinc, although phytates in grains can hinder absorption, so soaking or sprouting them can help.

Tips for Optimizing Absorption​

  • Pair Iron and Vitamin C: Consuming iron-rich legumes, greens, or fortified cereals with citrus fruits or peppers helps your body absorb iron more effectively.
  • Balance with Other Nutrients: High fiber or phytate content (in whole grains/legumes) can reduce zinc and iron absorption. Consider soaking, sprouting, or fermenting these foods.
  • Diverse Diet: Combining plant-based and animal-based foods can provide complementary nutrients and support balanced nutrient intake.

Monitoring Nutrient Levels​

If you’re concerned about your iron or zinc status—especially if you notice signs like fatigue, hair loss, or frequent illnesses—testing your blood levels is the most accurate way to assess whether you need more of these nutrients. This can help you fine-tune your diet and ensure you maintain healthy levels over time.

A simple, affordable blood test can give you a clearer picture of your iron (including ferritin levels for iron stores) and zinc status. If you’re curious or suspect a deficiency, it’s worth scheduling a test to stay proactive about your health.


 
Below you’ll find an overview of common supplement forms that contain iron, sulfur, or zinc. While there is no single “all-in-one” supplement combining all three in significant doses, many high-quality multivitamins and multimineral supplements will include at least some amount of each. If you suspect a deficiency in any of these minerals, it’s essential to confirm your levels with a blood test before you begin supplementation.


Iron Supplements​

  • Ferrous Sulfate, Ferrous Gluconate, Ferrous Fumarate: These are among the most common and well-studied forms of supplemental iron.
  • Heme Iron Supplements: Derived from animal sources, they may be better tolerated by individuals who experience gastrointestinal side effects from non-heme iron supplements.
Key Points

  • Iron requirements vary based on factors such as gender, age, and overall health.
  • Excess iron can be harmful, so it’s crucial to test your iron (and ferritin) levels before supplementing.

Sulfur-Containing Supplements​

  1. MSM (Methylsulfonylmethane): A popular form of supplemental sulfur believed to support joint health, skin, hair, and nail maintenance.
  2. NAC (N-Acetyl Cysteine): Contains sulfur in its structure and supports glutathione production, an important antioxidant.
  3. L-Methionine: An essential sulfur-containing amino acid typically found in protein powders or amino acid supplements.
Key Points

  • Most people get enough sulfur through protein in a balanced diet.
  • People interested in joint support or antioxidant support often consider MSM or NAC.

Zinc Supplements​

  • Zinc Gluconate or Zinc Picolinate: Popular forms that are generally well absorbed.
  • Zinc Citrate: Another option recognized for its relatively good bioavailability.
  • Zinc Sulfate: Contains zinc and some elemental sulfur, though it’s less commonly used as a direct sulfur source.
Key Points

  • Zinc deficiency can contribute to issues such as impaired immune function, hair loss, and slow wound healing.
  • Like iron, zinc can be detrimental in excess, so confirming low levels via a blood test is recommended before supplementing.

Combined Supplement Options​

  • Multivitamins/Multiminerals: Many comprehensive formulas include modest amounts of iron, zinc, and sometimes sulfur-containing amino acids. However, the amount of sulfur is usually quite small compared to dedicated sulfur supplements (e.g., MSM).
  • Targeted “Hair, Skin & Nails” Supplements: Often contain zinc and MSM alongside other supporting vitamins and minerals. Some may also include small amounts of iron (though it varies by product).
When considering any supplement:

  1. Test Your Levels: It’s always best to confirm whether you’re truly deficient (or borderline) in iron or zinc.
  2. Consult a Professional: If you have specific health concerns or complex medical conditions, talk to a healthcare provider or a knowledgeable nutrition professional.
  3. Watch for Interactions: Iron and zinc can compete with each other for absorption. If you need higher doses, you may need to separate them by a couple of hours.
  4. Stay Within Safe Limits: Aim for the recommended dietary allowances unless otherwise directed by your doctor.

Why Testing Matters​

Understanding your current iron, zinc, and other key nutrient levels can help you avoid unnecessary or excessive supplementation. If you notice symptoms like low energy, hair thinning, or frequent infections, a simple blood test could reveal whether low iron or zinc is a contributing factor. By pinpointing your exact levels, you can tailor your supplement strategy, ensuring you get the right nutrients in the right amounts.
 
 

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