[QUOTE = "Rain27, post: 157166, member: 38859"] I want to transfer enanthate from a vial to a sterile vial but here is testoviron and as an excipient it has
benzyl benzoate, does anyone know if it works as a preservative?
In my country I don't get benzyl alcohol and the testo comes only in blisters. Look on Google and the only thing I saw was that it is used for scabies, which I don't know if it works the same as benzyl alcohol limiting bacterial reproduction. [/ QUOTE]
Excipients
The vehiculum in oil depots is of course the oil. There are several types of oil that can be processed: sesame oil, arachis oil, castor oil and coconut oil (also known as medium-chain triglycerides (MCT)) (Table 1.2). All oils are derived from a mixture of saturated fatty acids.
The viscosity of the oil is relevant during administration because high viscous liquids cause difficulties to pass through a needle. Furthermore, it is a parameter that influences the diffusion coefficient, which will be explained in the next paragraph.
Besides the oil component, an additional excipient in oil depots is benzyl alcohol (BOH) (see Table 1.1). The main function in oil depots is that it enhances the solubility of the processed lipophilic prodrugs (Table 1.3). The second function of BOH is to ease the administration because of its viscosity reducing effect. The last function of BOH is that is acts as a local anaesthetic.
Other frequently used excipients are benzyl benzoate (BBA) and ethanol (EtOH). An overview is given in Table 1.3 below
Benzyl alcohol and Benzyl benzoate both act as preservatives.
