Anyone on 200mg + HCG without an AI?
- Thread starter smokedsalmon
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trt reznor
Active Member
Keep a close eye on your E2. I would think most guys would have issues at that dose.
antelopers
Active Member
My buddy does 100mg twice a week cyp and 250iu twice a week HCG with no issues besides a little bloating. His shbg is in the mid to high 40s. Personally that would be too much for me. Everyone's different. Give it a shot for 6 weeks or so?
I'm on 200mg of cypionate per week split into 2 injections. I use 400 IU's of HCG once a week(which seems to work for me). I take a quarter pill of aromasin the day after injection usually which keeps my E2 in check. My joints were hurting (due to low E2) so I quite my aromasin for roughly 3-4 weeks before my blood work and my E2 sensitive was at 115, lol.
Funny thing is.......I felt great!!! Joints felt amazing and didn't even know it was that high. I figured my E2 had risen to 50 or 60. I had no clue it would jump that high.
anyway, I went back on my aromasin to lower my E2 back down. I'll just cut down my aromasin a little when my joints hurt next time.
Funny thing is.......I felt great!!! Joints felt amazing and didn't even know it was that high. I figured my E2 had risen to 50 or 60. I had no clue it would jump that high.
anyway, I went back on my aromasin to lower my E2 back down. I'll just cut down my aromasin a little when my joints hurt next time.
BackToRegular
Member
Does high SHBG keep E2 from getting too high? I had mid range E2 and very high SHBG before starting at 200mg a week and 1000 HCG.
Vince
Super Moderator
I have used 200mg of testosterone cypionate, 100 mg twice a week. Along with 500 IU of HCG twice a week. And I've never used an AI. I wish I could find my labs at that time. I did feel good and had zero estrogen issues. The only problem I had was high HCT and that's the reason I went to daily injections, to lower my HCT.
For me it did not keep it from getting elevated, but the symptoms were not there.
The high SHBG keeps the free E lower just like it keeps free T lower.
BackToRegular
Member
Thanks BigBamBoo. Is this because high SHBG keeps free T lower (TRT or not) which means there is less free T to convert to E?
This is my understanding as well. Testosterone doesn’t convert to E2 in the blood, test aromatizes into E2 in the tissue, and free T is what’s activating androgen receptors in different areas in the body. So if free T is the only thing getting into the tissue to aromatize, then total T is irrelevant, again, from my understanding.
This is part of the story. Another part is probably the ratio of free testosterone to free estradiol: For fixed total or free testosterone, as SHBG gets smaller the ratio of free testosterone to free estradiol gets smaller. It is likely that guys can run into trouble when this ratio gets too small.
I am using 100mg test n 500iu twice a week. Its been 2 weeks. I am thinking to decrease the dosage to 150mg a week once my test levels are normal. In just 2 weeks i saw some changes so i think ill run this dosage for another month if my blood report comes normal. I dont care about estrogen levels unless its causing me symtoms
How you doing on this dose? Taking anything else? You inject 1x a week?
Charliebizz
Well-Known Member
Why would you add it back in if you felt great ? Over a number. If your important blood markers are good like lipids and your cbc why mess with a good thing?
Really, you wouldn't worry about having estradiol at 115 pg/mL? What about any other parameter at double an already high value? Admittedly the number should be verified, given that the sensitive test is notorious for spitting out crazy numbers. Nonetheless, if it's in the ballpark I don't think I'd be choosing to experiment on the long-term effects of ultra-high estradiol.
Charliebizz
Well-Known Member
What could the long term side effects be if cbc and lipids are in line. I’m not here to argue at all but there is a lot of merit to the new way of looking at e2 serum and I see a lot of men actually doing pretty well on trt when they have stopped worrying about e2 levels. It’s a hell of a lot worse to have low e2 that’s for sure
Hormone levels are associated with U-shaped mortality curves. I wouldn't want to be the one testing whether or not these relationships are causal.
Charliebizz
Well-Known Member
Like I said if all the indications of mortality are in line is it really a worry ?
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