Thanks Systemlord. I just read that study, and it has a conclusion that efficacy (response) of exogenous Testosterone is correlated to androgen receptor health:
"Genomic and non-genomic effects, androgen receptor polymorphism and intracellular steroid metabolism further contribute to such diversity [with the time-course of the spectrum of effects of testosterone]."
Unfortunately, it did not discuss a method of correlation. Obviously, it is a positive correlation, but I would be interested in a study that can predict the time-course and level of response based on the subject's AR "health" (which would require the ability to test the AR system).
There are many people who suffer from AR suppression after use of certain drugs (e.g., Post-Finasteride syndrome) and do not respond well to TRT (the ARs cannot make use of the T).
So two things:
1. Is it possible to predict how well and how quickly someone will respond to TRT based on a measurement of AR "health"?
2. Is it possible to boost/improve the AR system (SERMs? I don't know much about them)?