Allergic reaction to oils

[mooseman109]

I have a friend who is having allergic reactions to testosterone cypionate injections He gets a fairly large itchy rash about 3” across. If he takes an antihistamine there are no problems. Injection sites have been sub q in belly and IM in leg, results are the same. He started with grape seed oil and went to sesame seed oil and is now starting cottonseed oil. The first 2 created the same problem, just started cottonseed yesterday. That stuff is over double the price.
Has anybody encountered such reactions? I M curios if it is the oils or the drug itself

 

[Vince]

I have a friend who is having allergic reactions to testosterone cypionate injections He gets a fairly large itchy rash about 3” across. If he takes an antihistamine there are no problems. Injection sites have been sub q in belly and IM in leg, results are the same. He started with grape seed oil and went to sesame seed oil and is now starting cottonseed oil. The first 2 created the same problem, just started cottonseed yesterday. That stuff is over double the price.
Has anybody encountered such reactions? I M curios if it is the oils or the drug itself

It's usually always the oil

 

[madman]

I have a friend who is having allergic reactions to testosterone cypionate injections He gets a fairly large itchy rash about 3” across. If he takes an antihistamine there are no problems. Injection sites have been sub q in belly and IM in leg, results are the same. He started with grape seed oil and went to sesame seed oil and is now starting cottonseed oil. The first 2 created the same problem, just started cottonseed yesterday. That stuff is over double the price.
Has anybody encountered such reactions? I M curios if it is the oils or the drug itself

Yes there have been some cases where one will have a bad reaction to the ester but I would say the carrier/excipients of the formulation are the usual culprits.

Post in thread 'Carrier Oil/Ester Question Grapeseed vs Cottonseed'

Dec 15, 2024

Hello - I've been getting my testosterone from a compound pharmacy which is cypionate in grapeseed oil. I now have insurance and can get it for a significant lower cost through a CVS pharmacy. It wasn't clear at first what the testosterone was suspended in but I had to read through the massive information packet to find out:

Testosterone Cypionate 200mg
Benzyl benzoate .2ml
Cottonseed oil 556mg
Benzyl alchohol 9.45mg

Is it worth paying a premium for grapeseed oil or saving a $100/month or so and going with cottonseed oil?

Welcome to Nelson's house!

The standard carrier for TC...

• madman

Post in thread 'On TRT for 3+ Years. Now I have extreme itching'

Dec 25, 2024

I just spent a bunch of time today with my doctor and retraced old labs and try to align my symptoms with my timeline

It appears that I got off of my Pharma test at some point a year ago and wound up getting my test from a local source and that is what my issue started happening

After some discussion today with my doctor, we determined that my original testosterone source was from a compounding pharmacy and they use different preservatives. I believe that it’s possible that I might be allergic to something in the mass produced test causing my allergic reactions.

If you are one...

• madman

Thread 'Delayed hypersensitivity reaction to testosterone cypionate injections'

Jun 27, 2024

Testicular hypergonadotropic hypogonadism is a disorder characterised by insufficient or absent production of testosterone by the testes in the absence of a hypothalamic or pituitary problem causing delayed or absent puberty. Injections are initially the preferred route of administration of testosterone for puberty induction due to their ability to titrate the small initial doses that are appropriate for puberty induction.1




CASE REPORT

A 13-year-old male with a history of testicular hypergonadotropic hypogonadism presented to our clinic, reporting a red, itchy...

• madman
• testosterone; adverse drug reaction; acd
• Replies: 1
• Forum: Testosterone Side Effect Management

• 

Allergic contact dermatitis (ACD) to testosterone is rare and only two cases have been reported.5,6 In these cases, patients raised suspicion of testosterone ACD following reactions to Andropatch® placement and were patch-tested to different testosterone formulations and Andropatch® excipients, including ethanol. Results showed positive reactions to testosterone propionate and undecanoate5 in one case and to testosterone enanthate and undecanoate in the other.6 To our knowledge, this is the first reported case of a delayed-type hypersensitivity reaction to testosterone cypionate.

ACD to excipients in injectable testosterone preparations has not been reported. A case of anaphylaxis secondary to benzyl benzoate in testosterone injections was described,7 but our patient did not have an immediate reaction and instead developed delayed reactions, consistent with Type IV rather than Type I hypersensitivity reaction. With injections being a common route of administration of testosterone, clinicians should be aware of the rare setting of delayed hypersensitivity to testosterone cypionate, one of the main formulations. In the setting of allergy to testosterone cypionate, alternative injectable formulations can be considered

 

[Gman86]

Big pharma is for profits over everything, unfortunately. So they’re going to use the cheapest ingredients possible, in their products. Same with compounding pharmacies. The UGL source I use actually uses way healthier carrier oils and excipients. Again, really sad that this is the case. It’s the same with food tho. Big companies are going to use the cheapest/ most harmful ingredients possible, to increase profits as much as possible. It takes small mom and pop type companies to make the same/ similar foods, but with healthy/ more expensive ingredients. Same with UGL’s. They’re the only place ur going to find AAS made with human grade MCT oil, which as far as I know, is the best carrier oil that can be used. Really wish we could just pay more and be able to get pharma grade AAS made with MCT oil, and healthier excipients.

 

[madman]

Big pharma is for profits over everything, unfortunately. So they’re going to use the cheapest ingredients possible, in their products. Same with compounding pharmacies. The UGL source I use actually uses way healthier carrier oils and excipients. Again, really sad that this is the case. It’s the same with food tho. Big companies are going to use the cheapest/ most harmful ingredients possible, to increase profits as much as possible. It takes small mom and pop type companies to make the same/ similar foods, but with healthy/ more expensive ingredients. Same with UGL’s. They’re the only place ur going to find AAS made with human grade MCT oil, which as far as I know, is the best carrier oil that can be used. Really wish we could just pay more and be able to get pharma grade AAS made with MCT oil, and healthier excipients.

This is pure nonsense!

There are no major health benefits when it comes to MCT being used as the carrier oil as any oil whether (cottonseed, sesame, arachis, grapeseed, castor) being used by big pharma let alone any reputable compounding pharmacy are pharmaceutical grade and higly refined/purified.

Even then if one used human grade MCT oil as the carrier other than its low viscosity which will make drawing/injecting a breeze the nutritinal benefits hold no f**king weight here as the amount of the oily solution one is injecting whteher following a once weekly protocol or injecting more frequently is miniscule!

We are talking a measly 1 mL of the oily solution/week at best!

The majority of men on TTh are injecting 100-200 mg/week and some <100 mg/week!

The most commonly used esters are TC/TE 200 mg/mL strength.

Now if we are talking diet and consuming fats then we can get really deep here when it comes to saturated (long, medium, short-chain), polyunsaturated, monounsaturated let alone the most critical fats when it comes to health the polyunsaturated Essential Fatty Acids (EPA/DHA/AA)!

You need to stop hanging out on those mickey mouse forums let alone watching all those kiddie videos on the net!

Still clueless after all these years!

Stuck on re-runs here.

Post in thread 'Testosterone mixed with MCT oil'

Apr 30, 2021

I am currently take shots of Testosterone Cypionate which is mixed with grape seed oil. A great deal of current scientific research is revealing that these industrial seed oils are toxic and a major source of modern diseases such as heart disease.

I have heard that it possible to purchase Testosterone Cypionate mixed with MCT oil but I do not know what company sells it. Can anybody help?

Stop and think this through.

First off the carrier oils used are highly refined/purified.

More importantly, the amount of oil you are injecting weekly when on trt is minuscule!

The...

• madman

• 

Post in thread 'Testosterone mixed with MCT oil'

Apr 30, 2021

I will ignore the condescending tone of your post and reply.

In 2017 I weighed close to 300 lbs. I was a type II diabetic and took Metformin, Glipizide, and daily shots of insulin to control my disease.

I am a firm believer in evidence based nutrition. As of this date the overwhelming evidence is that the vast majority of modern diseases such as heart disease, cancer, diabetes, Parkinson's Disease etc... is associated with insulin resistance.

Insulin causes the body to burn glucose instead of fat. When we are insulin resistant our bodies are forced to produce excessive insulin...

• madman

• 

Post in thread 'Testosterone mixed with MCT oil'

Dec 10, 2022

Every oil is different in viscosity and nutritional value but some oils are dirt cheap to produce thus extremely profitable. I do my own home-brew and my Ester of choice (Oil) is Coconut C8 and it is hella expensive but worth it because it has great nutritional benefits. I am also my own lab rat.

There are too many knuckleheads that believe what they are told by a dumb-shit Doctor, a person who owns a practice who got brainwashed by society. Lookup the word "Practice." Doctors practice not cure. Nobody sells Coconut Oil Testosterone because it's not profitable enough, you have to make...

• madman

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[madman]

Big pharma is for profits over everything, unfortunately. So they’re going to use the cheapest ingredients possible, in their products. Same with compounding pharmacies. The UGL source I use actually uses way healthier carrier oils and excipients. Again, really sad that this is the case. It’s the same with food tho. Big companies are going to use the cheapest/ most harmful ingredients possible, to increase profits as much as possible. It takes small mom and pop type companies to make the same/ similar foods, but with healthy/ more expensive ingredients. Same with UGL’s. They’re the only place ur going to find AAS made with human grade MCT oil, which as far as I know, is the best carrier oil that can be used. Really wish we could just pay more and be able to get pharma grade AAS made with MCT oil, and healthier excipients.

Again as I stated in a previous thread!


The nutritional benefits are moot and even then the amount of oil being injected is minuscule!

Would not even waste my time fretting over the nutritional properties.

If anything you would be far better off stuffing some extra virgin coconut oil down your piehole.

You know that crude/unrefined/unpasteurized oil which contains a large percentage of health-promoting lauric acid.

You can nitpick over the viscosity or possible allergic reactions to certain carrier oils but fretting over the nutritional benefits is f**king absurd!