Stanozolol has been associated with serious hepatic sides, oxandrolone has not at least that I've seen in any studies if used alone in clinical dosing. Still longer term nandrolone is likely to be lower risk than OX esp for sarcopenia, certainly less than STAN and STAN at least according to the abuse group makes joint pain worse, not better. I think if we put OX through the same level of animal research that nandrolone has gone through, we'd see similar results and not in a positive light. The dose is the poison combined with genetic response.