Abstract
The purpose of this study was to test a hypothesis that T3 promotes glucose uptake via enhancing insulin-induced Akt phosphorylation and VAMP2 translocation in 3T3-L1 adipocytes. T3 significantly enhanced insulin-induced phosphorylation of Akt, cytoplasma to cell membrane translocations...
Hi everyone
I'm 46 and i've been suffering from decreased sex drive since I turned 40("Life begins at 40 eh?") before that I always considered myself to have a very healthy sex drive.
Three months ago I was travelling and decided to get one of all these comprehensive medical checks, it was...
Fellas, often do you inject? Has it had a impact on your thyroid? I started in April of 2020, and last year around October I started having problems, and now I can connect them to TRT. It seems it somehow Impacting my thyroid function. I just went up to 112 mcg, and I dont have a problem with T3...
I've been popping half a gram of l-tyrosine with my t4 each morning, temperature rises much faster. Reading 98.x most mornings by 7:30. Any drawbacks to this?
Most nights I wake after a good nap. Last night about 2:30 woke right up. Maybe most people wake but return to sleep quickly perhaps. I was up until 4ish. Theanine wasn't enough to go back down. I decided to take T4(50ug) at that time. Takes about an hour I guess but woke sleeping like a baby...
As most of you on this forum know from my other posts that I have been on TRT for about 11-12yrs now and never felt dialed in.. Suffering from mild depression, lack of sleep, no motivation, cognitive issues, etc.... So I was recently going over my current and past blood labs to see if there are...
Optimal FT3 should be anywhere around 3.7 to 4.2 or so. Has anyone noticed more difficultly to build or hold muscle at this level range?
Should perhaps an ectomorph interested in muscle building think twice on optimizing FT3 at these levels?
Below are my Lab results from my use of Test Cyp @ 20mg ed/SQ for 8 months and Test Prop @ 15mg ed/sq for about 3 months.
Test Cyp @ 20mg ED/SQ (8 months)
Testosterone Total-Male
609.0 ng/dL
300.0 - 890.0 ng/dL
Free Testosterone
168.7 pg/mL
47.0 - 244.0 pg/mL
Estradiol, Serum
72...
If t3 is the active thyroid hormone, then what would be the point of even taking t4? I ask because I have been on t3 only treatment since beginning HRT due to high RT3. Wondering if I could benefit from adding in a little t4 to my protocol. T4 is usually at the bottom end of normal or just...
I'm curious how many TRT recipients on these forms also have thyroid issues. It seems that many people I know who are on TRT are also on thyroid medication, I'm wondering if the two are related. Does TRT eventually lead to thyroid issues?
How's it going everyone? I have a quick question regarding thyroid testing. You have to wait 24 hrs after your last thyroid dose and then get labs. I take an AM and mid day dose. Does this mean I need to take two separate sets of bloods drawn (in the AM and mid day). That way both tests are...
I know it is late question.. Week ago I jumped on 25mcg of levothyroxine because of some sides…
I am on trt for few years and have really low SHBG - 8,8 so most of those sides could be because of bad protocol.
Anyway sides are - hair loss, low sexdrive + ED, bad mood, tiredness, and morning body...
Got my blood work back from taking 2 grains of Armour Thyroid every morning. Recommendations? Lower the NDT and add cytomel?
TSH (0.45-4.5): 0.859
T4 (0.82-1.77): 1.48
T3 (2.0-4.4): 4.4
RT3 (9.2-24.1): 25.4
Thank you in advance.
Does somebody here managed to deal with elevated Reverse T3 and what was causing it in the first place?
FT4 is at the top of the range even can go above if I overdo the selenium, regularly supplementing selenium, zinc, vitamin d etc. FT3 is a bid mediocre(around 2.9-3.3ng/l in range of 2-4.4)...
I read someone in another thread mention that without enough iron, T3 can’t get into the cell. I’m familiar with the usual things you’d read on Thyroid and iron levels, and am wondering if anybody would know if it was involved in more than just helping convert T3 to T4 in an abstract way, and...
Been on HRT for a few years and still ironing out some lingering issues. Historically I can get my total T to 1300ish with a 200-215 free T and 50-57 E2 without an AI or anything with daily small injections of testosterone and HCG. My free T3 on labs is usually a little low (3.0-3.2), my rT3’s...
For anyone with experience with injectable L-Carnitine:
Do you take it WITH carbohydrates? Fasted? I have heard mixed things here. Some say it’s a waste to take without carbohydrates, some say at can be taken fasted.
Any negative interactions with thyroid medication? I've heard it...
My TSH has been elevated for years, and even though I have several classic low thyroid symptoms — sluggish in mornings, intermittent brain fog, the early afternoon crash — I've avoided going on thyroid meds because my free T3 is always right in the middle of the range.
For my latest set of...
I am in a gray area with borderline labs that functional medicine doctors would say may benefit from thyroid meds. I have started and stopped T3 a few times, primarily due to side effects. My biggest concern is I have noticed a low grade headache. Either my body does not want or need extra T3...
Hey guys,
I'd like your input on whether I need Thyroid treatment or not. I'm 33 years old. My TSH has always been high since before starting TRT in my late twenties. I've posted all labs below in order from the most recent to the oldest. I am experiencing moodswings (2 days good, 5 days bad)...
Anybody have any theories on why one guy does great on 100mg test/wk and others (like myself) struggle to get their say free test in a good range? I remain curious. Could adrenal or thyroid be a reason?
High hematocrit, low ferritin and thyroid.
Does taking 15 mg of ferrous sulfate increase ferritin?
Hello everybody. I will attach my exams below and I would like your opinion. Thank you very much.
In early January of this year I had a phlebotomy due to an increase in hematocrit. I only did...
I’m wondering if anyone has noticed less of an effect from time release T3? I switched to time release T3 this fall from the quick release version and I just recently had a full panel of labs done. To my surprise my rt3 had creeped up to 20.8 (9.2-24.1) and my TSH to 2.6 (.450-4.50). No...
I began supplementing DHEA at 25mg every morning after lab work showed it at 95. Libido, sleep, morning wood, erection quality all seem to have improved. I've noticed no ill side effects from it.
Something that concerns me is my most recent labs show a significant increase in TSH. TSH has...
Who is currently taking thyroid meds? If so, my questions are as follows:
1) did you notice an increase in energy level ?
2) Did you notice an increase in your mood? Are you in a much better mood?
3) do you notice you burn fat easier?
4) did it improve your cholesterol levels?
thank you in advance.
I am a final year med student and have been replacing my hormones for multiple years. I post this because I want to raise awareness that it is not just testosterone. One thing I frequently notice, is that many males are really fixating on testosterone (e.g. whether adding HCG or different doses...
Since starting TRT over 10 years ago, I have always for the most part had messed up blood panels such as HDL/LDL level.... For the past year I have been on Thyroid (Armour 2 grains per day) and my blood panels have come back all in range.... my LDL/HDL was near perfect... I started Thyroid to...
Hey, I am a final year medical student. For years I had life-impairing fatigue due to low-cortisol issues.
After doing a LOT of research, I collected a list of methods we can try to raise our cortisol naturally and therefore to help get rid of HPA-dysfunction. I share this here because I am...
I’m wondering if anyone has felt better without thyroid meds? I started t3 prior to trt due to elevated rt3. I’ve been on trt just shy of 2 years and still can’t find a balance. I generally test high on t3 and mid to low on t4. Been feeling really fatigued and lethargic lately. I trust Dr...
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