progesterone

is there any difference for Pregnenolone bypassing the liver on downstream metabolites? is there less conversion to Progesterone? I heard once Dr John Crisler, mentioning how oral pregnenolone may be better for people with anxiety, because it gets converted more into allopregnenolone with the...

Hello, Does anyone have any experience with Nandrolone only + Micronized Progesterone? I've been told its really good but want to see others opinions before trying it thanks

Do we know if there is an optimal Progesterone level in men? just a curiosity, I couldn't find anything on line

Hey guys, Been working on trying to reduce my water retention and seem to have hit a brick wall. My estrogen is not too inflated but believe that it may be causing some of my issues. After reading some threads on sodium/potassium ratios I cut out a large potion of my added salt and doubled my...

Just wondering if pregnenolone has been the missing puzzle piece in anyone’s protocol, and if things finally clicked when they added it. Thanks.

The short story is that meet Total test is about 600 on 100mg IM every 5 days. I still have alot of anxiety, mood issues, tremors, fatigue, Ed, sleep issues, blood pressure high, etc. I am even having some hoarseness in my throat near my thyroid. I'm trying to look at other hormones that could...

At age 33, After years of depression, anxiety, fatigue, weight gain, sleep problems, ed, etc. I convinced my doctor to test my hormones. I was specifically interested in my Cortisol levels due to prolonged profound amounts of physical anxiety. The results of what he tested were; Total...

Hello, anyone else here whos libido goes down with pregnenolone? I use 50mg day and its totally kills my libido and erection, it took a while to figure it out. Same thing happened with even smallest dosage 500iu/wk hcg in a past. Probably im sensitive to increased progesterone from pregnenolone...

Hi, I have the symptoms of high E2 (bloating, mild gyno, ED, low libido, irritability, etc). I have been using Anatrozole but it is a fucking hit or miss, the times I ever felt good tye most it last are from a few days to a few hours. I have also tried to try with lower doses and no AI, but no...

 Due to not using HCG for 3 Years (Just testosterone), according to Nelson, this can cause your Pregnenolone and Progesterone levels to crash. My theory is due to having very low Progesterone it is causing Estrogen Dominance and any time I take HCG I am having estrogen side effects even...

Hello everyone. Following my failed attempt at restarting my natural testosterone production, I'm back on HRT in the form of 500iu HCG 3x p/w. ---------------------------------------------------------------------------------- Current issues: Always cold, especially extremities Absent Libido...

Progesterone is often prescribed for postmenopausal women to take during certain days of their cycle. What about women who have undergone endometrial ablation? It’s virtually impossible to tell what part of their cycle they are in. Do they just take a small dose every day? Or just stay on a...

My wife and I are traveling for the next 5 days. She takes Estrogen cream nightly and 50mg of Progesterone. She packed the estrogen but left the progesterone on the table. Just wondering if anyone knows if its safe to skip the progesterone for 5 days and just take the Estrogen. Conversely she...

I’ve seen various accounts of men on TRT with deficient levels of progesterone -- many of whom had normal levels prior to treatment. LH is important for leydig cholesterol -> pregnenolone conversion, and also for adrenal steroidogenesis. HPTA suppression and the subsequent absence of LH is...

Per my consult, I may be trying 10mg oral Progesterone nightly. But, online all I see is TD creams. Anyone have a good source?

So trying to figure out why I'm having on/off ED issues. Currently on scripted 200mg test E and 1mg adex, split into twice weekly doses. I pin sub Q Mon nights and Fri mornings. Blood was taken Thursday afternoon. Anything here that might be linked to ED/libido? I see Progesterone is at the...

Basic Info I'm 6 days into a major protocol change overseen by Defy Medical and feeling really strange and unsettling side effects. There are some confounding factors that are making it hard for me to know what to do. Defy is closed for a few days for the holiday so I can't get a consult and...

Did anyone used progesterone successfully for better sleep? Especially to stay asleep at night and to calm down the mind. I've been tested for progesterone and the level was 0.10 ng/mL (range 0.10 – 1.00 ng/mL). Several TRT doctors refuse to prescribe progesterone due to be highly inflammatory...

I've been doing reading on water retention on TRT and I'd like to discuss a hypothetical I haven't seen floated: that the ratio of progesterone to estradiol could play a role. This is a good post by Nelson: "Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol". The...

My daughter tried IVF last year (unsuccessfully) and has a few boxes of Menopur menopropins and Progesterone left over. Is this a brand name drug thats really HCG? My doctor may put me on HCG soon and I was planning to bring them in to him ask him about this. Does anyone know if this is the...

I was surprised 17-OH Progesterone was low <10 on LabCorp scale 27-199 ng/dl considering along with TRT I'was on HCG 125Iu daily 50mg Pregnelonone and 25mg of Hydrocotisone I actually thought because I'm on Hydrocortisone Progesterone would be high(er) Why would that be low?

Hi. My mother started hrt recently (T injections 2x5mg/week. Estradiol patch 3.8mg (replace it every 7 days) and oral progesterone 100mg every day) She is 56 in menopause Her labs on this protocol are T>> 116ng/dl 2 days after injection e2>> 30 pg/ml...

I've researching a lot on how to improve physical and mental wellbeing. I've been watching a lot of Dr. Crisler videos where he explains how important it is to keep all of the "pathways" open that are shut down using TRT by using these supplements. Does anybody use DHEA with Progesterone? Has...

I seem to have higher than normal DHEA and Progesterone. What are some things to look into regarding possible cause(s)? Most recent results: https://imgur.com/a/2A6ac Protocol: 15mg Clomid ED (high DHEA and Progesterone predates Clomid usage) 40 y.o., good health

So from my understanding, progesterone lowers DHT as well as keeps E2 in check, amongst a bunch of other benefits. This is a possible explanation why young men with high natural test don't have issues with baldness and elevated E2 issues. It's their normal/ high levels of progesterone keeping...

Had my wife run some bloodwork. She's in the luteal phase of her cycle and I noticed that her estradiol is about 50% higher than the high end of range... Not sure if this is something to be concerned about or could simply be a case of 'estrogen dominance'. Guess we need to run progesterone...

I was listening to a podcast with Dr. Tami Meraglia. During the podcast Dr. Tami mentioned that instead of Anastrozole she would consider giving men Progesterone since it helps stop conversion of T to E2. Also, said Progesterone replacement in men helps with irritability. Anybody taking...

One of the truly wonderful things about using compounded bioidentical hormone therapy is the opportunity to choose from a wide array of dosage forms. A “dosage form” is the manner used to deliver a medication into the body, such as capsules, creams, lozenges, gels, suppositories, and drops...

Skin Deep Look At Hormones Written by Michelle Violi, Pharm.D – Women’s International Pharmacy There is no doubt that hormones affect the skin, but do different hormones affect the skin differently? Let's take a closer look. Estrogen Estrogen appears to affect the skin and its appearance...

My last bloods came in with Progesterone (<0.25-0.56) 1.87 ng/mL - over triple the higher end of the scale. I've been searching, and can see that elevated Progesterone messes with things like libido, energy levels, sleep, is a precursor for T and E, erectile function etc. However, I can't...

Hello, I've had libido and erection issues off and on for at least five years. During the same time frame I've also experienced periods of melancholy mood. I have a bit of anxiety but I've not needed medication. My sex drive and erection quality have both taken a huge dive over the past 12...