estrogen

First of all--thanks for the amazing and science/data driven advice I've received from you guys! I totally agree with treating symptoms not labs, but I've got some results that I think warrant action. Latest labs attached. Any help or questions much appreciated! General background: strict...

Has anyone experienced eczema like skin issues while on TRT? I don't mean injection site issues like redness and inflammation but systemic hive like, extremely itchy raised lesions on the back, chest, right and left flank. I have been off TRT for a few months now and the issue has increased. The...

Here we go - I’m off on an estrogen trip again. I am getting labs tomorrow, but results have been taking 10-14 days. I don‘t think I can remain this miserable for that long. I am on .1 Enanthate daily, and .125 Anastrozole every other day. I was taking .125 every 3 days, and my e2 was at 31, so...

Hey guys, Looking to get some input. I am 34 years old, low SHBG (17-19), 160lb, athletic build. I've spent the last year experimenting different protocols to find one where I feel good/normal. Surprisingly, the closest I can get to feeling fine is on a single injection frequency, with AI every...

Hello, for the past 2 weeks I’ve been using progesterone cream, one pump scrotal application per day. Over this weekend I started to notice my joints were achy, felt sort of dry, popping a bit. I’ve actually been feeling pretty good (libido and mentally) but thinking I may have overdone it with...

Say in theory somebody is on exogenous testosterone and crashes their e2 with arimidex. Would this result in the production of LH even though they are on testosterone due to negative feedback (low estrogen)? Not that I would ever do that but just curious how the feedback loop would play into this

After utilizing a 24 mg EOD protocol, my estrodial is still high. I'm thinking this may be why I am having some ed issues still. Lab results right before next injection: Testosterone total (MS): 587 ng/dl (250-1100) Testosterone free (dialysis): 139.5 pg/ml (35-155) Estrodial ultrasensitive...

I've been reading a lot of good things lately about calcium d glucarate particularly in it's effectiveness of estrogen control. Just wondering if anyone on here has used it and can share their thoughts on it?

Hi all, I'm about to start enclomiphene (in 9 days) and I'm still trying to figure out if I should start anastrozole at the same time. I am confused because in various posts and studies there seems to be conflicting information about whether EN raises or lower E. In some studies it says it...

What is a good way to control estrogen when anastrazole is too powerful? I was taking 80 mgs of testosterone 2 x a week when my estrogen went through the roof. I started taking .125 mgs of anastrazole 2 x a week and it brought my estradiol down to an 8 and total test was at 854. Can anastrazole...

Been on HRT for a few years and still ironing out some lingering issues. Historically I can get my total T to 1300ish with a 200-215 free T and 50-57 E2 without an AI or anything with daily small injections of testosterone and HCG. My free T3 on labs is usually a little low (3.0-3.2), my rT3’s...

Quick question. I just restarted TRT after an approximate 5 month break for fertility reason. Im on HCG (250 twice per week,) and 120ml weekly shots of test E (divided in two subq weekly shots.) I just received my blood work and my resultare as follows: Testosterone 20nmolL Testosterone 576...

It's pretty much the only hormone that I haven't tried. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854098/

Is it possible to increase testosterone level with only Anastrozole? If a person is not on TRT.

Anyone know what it means or what it is indicative of when the penis is semi hard through sex or masturbation and then ends up getting erect right before climaxing and during. Low E? high E? This happens sometimes while other times it works fine..

Hi everyone, In the past, I used to supplement with zinc nitrate. However, I recently heard that zinc picolinate may be better while being on TRT. Would you guys recommend zinc picolinate over zinc nitrate to lower estrogen levels? My estrogen is not too high at the moment, but my dr recently...

Looking for some advice please. Current Protocol 100mg 2x weekly 500iu HCG 2x weekly No AI (Discontinued. It was 1mg 2x weekly and I felt it gave me mood swings) Latest Labs Total Testosterone >1500 E2 69pg/mL Notes: I'm not sure if the E2 test was sensitive or not, the labs don't show...

My old dr was a dr who was all about not treating E2. He said let it go as high as you want and it won’t be a problem. Well I am seeing a new dr now and my e2 sensitive was 45. My libido has been super low, my anxiety kind of high, also my junk shrivels up to nothing along with my scrotum...

I don't think this has ever been discussed, but it might be important for those of us that often wake up from sleep. Oral contraceptive contain estrogen and progestin, (progestin is an analog of progesterone) which have been shown to increase the elimination half life of caffeine from 5-6 hours...

Increased Endogenous Estrogen Synthesis Leads to the Sequential Induction of Prostatic Inflammation (Prostatitis) and Prostatic Pre-Malignancy Stuart J. Ellem,* Hong Wang,* Matti Poutanen,† and Gail P. Risbridger* Prostatitis causes substantial morbidity to men, through associated urinary...

I have a question in regard to estrogen levels on Test cypionate and Hcg combination with the use of 5 mg of Cialis daily. For those using 5 mg of Cialis how much would you say that Cialis has lowered your estrogen levels as compared to when you did not use it on the same protocol?

So I inject 100mg weekly and I’m about to split my dose but until then I got my bloods back and e2 was high. I’m curious about how off this ratio is though? 2 days after injection T is 1066. 4 days post injection T is 865 and E2 ultrasensitive is 59pg/ml. I’m waiting on trough results.

I take 100mg once a week just got my sensitive e2 back 4 days after my shot and it was 59 range is less than 29. My Test level hasn’t come back yet but I’m freaking out because it explains why I’ve been breaking out. I could only imagine what my e2 is at the day after my shot. Should I split my...

A tip of the hat to "PakMan" at PeakT for the reference to this article. The underlying work is on mice, but may have implications for humans. Summary: Researchers have uncovered specific regions of brain tissue where aromatase is present, that drives male sexual desire. Aromatase converts...

It is the Estrogen or DHT that make men have problens in prostate when get older or by hormones use? Older guys on trt here, please share if you are having problems with it. I want to understand about this subject.

I’ve been on TRT for about a year now and taking test 200 cyp @ .4 2x a week along with HCG @ 500 iu’s 2x a week. Started taking anastrazole .125 2x a week about 8 weeks in because a lump develop under nipple. Took tamoxifen, started anastrazole and it cleared up. Fast forward approx 6-8 months...

I have been on TRT for 15 years. I am waiting for my HCG prescription to arrive and feel comfortable adding that to my regimen. Since my doctor is not an Endocrinologist, he is prescribing Estrogen blockers and TRT. My question is if I take TRT/HCG, do I still need the estrogen blocker? I...

Greetings, I have a TRT patient at my clinic and the fellow providers nor myself can figure this out. I have a patient who had a total Estrogen level of 20,240, with a TT of 420 and FT of 12. I had the other provider to run sensitive estradiol on him and he is pitifully low at 3.4, I had them...

Hi everyone, first post but have greatly appreciated everyone’s comments on the forum that I have been reading through. I am having some frustration getting my protocol dialed in. Started TRT 1.5 years ago and have been using Testosterone Cypionate and all injections SubQ. Blood work and dosage...

See attached. I recentlay had bloodwork done, and my Ultrasensitive Estradiol came back at a 4. Typically, I would say this is low, however, they showed a range of <29. Accroding to them this was in the “Green” zone, and I am good to go. I am not buying it. What are your thoughts? I wasn’t...

Question - has anyone found there to be a correlation between the amount of fluid released during ejaculation, and estrogen levels?