depression

Hello, has anyone here experienced heart palpitations, fatigue, low energy, muscle pain, or depression because of hormone imbalance?

Been on trt for 4 years now. Testosterone level 522, estradiol at 36. dosing EOD 90mg a week. I have been developing depression and anxiety more than usual last 3 months. I was also on 400iu of HCG i9n the past but discontinued as it made my anxiety worse. I was wondering if I should be asking...

This might seem stupid, but here me out…. Long story short: I have treatment/lifestyle/therapy resistant depression, mental fatigue, anxiety. You name it, I’ve tried it. Believe me. Both medical and underground. Doctors are at a loss. But one day I decided to try testosterone and….. bam. Total...

Nandrolone is literally the only thing (so far) that helps me manage shoulder pain due to my cervical radiculopathy. But even at low doses (~60 mg a week), I seem to get very depressed on it, and feel "flatlined" about life in general. Good news is that even at 60 mg it helps immensely. I've...

Thought I would start a discussion about this awesome lesser known peptide, yet one of the peptides with quite a few actual human studies behind it. So I'll start with my experience before getting to the science: I have done a few cycles (they last 5-7 days of 8-10 mg) of it this year and...

I have been treating with multiple medications for depression for the past 4 years. I began TRT 18months ago after having my prostate removed due to cancer. in reading in this forum, I see that most men report their motivation and sense of well being improve while on TRT. Although THT has...

So I have been feeling pretty crappy lately (down depressed anxious and no libido) and decided to do labs. I had labs done and my t was -1319 E2 sensitive was - 31 Shgb- 42 Free T was 29 But the weirdest one was my dht it came in at 50pg/ml. Which is incredibly low. What makes no sense is I’m on...

Good evening, everyone. I figured I'd make a thread documenting my progress. Hopefully the information and ensuing discussions contained herein could provide assistance for others down the line, as others' threads had provided for me. I also have some questions which will be added at the end, so...

I decided to create a new thread to compile some of the evidence against the use of antidepressant drugs to treat depression. In my mind, the most compelling reason to avoid them is that they may worsen the condition over time, so we will begin there. The following paper suggests poor-long...

I added nandrolone officially to my regimen about one month ago (I have tried it in the past but never very long). The purpose of adding it was to assist in resolving joint pain, and it works PERFECT!! 10 out 10, joint pain is nearly non-existent! I am doing physical therapy in addition...

It is often assumed that the effects of antidepressants demonstrate that depression must be at least partially caused by a brain-based chemical abnormality, and that the apparent efficacy of SSRIs shows that serotonin is implicated. Other explanations for the effects of antidepressants have been...

A new preclinical drug reported by James Bibb, Ph.D., and colleagues has the potential to combat depression, brain injury, and cognitive disorders. The drug, which is notable for being brain-permeable, works by inhibiting the kinase enzyme Cdk5. Cdk5 is an important signaling regulator in...

I’ve spent the better part of the last 2 years struggling with persisting ED, Depression, Anhedonia following the use of Boldenone and then Primobolan. My symptoms align mostly with what a lot of people with PFS have but given I’ve never had PFS I’m reluctant to post on the propeciahelp forums...

I was reading that cabergoline increases dopamine so it can be used to treat depression. My brother's doctor prescribed him 0.25mg per week. What do you think ?

For years I have dealt with treatment resistant depression. TRT has helped a bit, but it’s no magic bullet. I’ve been reading up on a medication called Parnate. It’s an MAOI and is apparently very successful at treating TRD. The only issue is mainstream doctors are hesitant to prescribe it, so...

Just curious if anyone felt/had symptoms of depression after starting TRT? I am 10 years in on TRT and I have felt mentally tired and unmotivated most of the entire time... I sometimes thought it was High E or low Thyroid but no matter how much I lowered E or adjusted thyroid (Armour) it...

I have noticed over the years like clock work a distinct drop in my mood (mildly depressed) on days where the sun is not out. I am more of one of the just “deal with it” guys and chalked it up to being normal but the positive effects sunlight has on my mood are too noticeable to ignore. I...

"A previous study showed that laughing gas improved depression symptoms one day after treatment. In the new study, the researchers wanted to see whether those effects were long-lasting and whether a lower dose could work as well. To do this, they recruited 24 patients with TRMD, who were...

All, I have friend who states that after orgasm from masturbation, will feel depressed, crappy, etc, but doesn't after orgasm during intercourse. He also asks about his refractory period. He states : "Vulnerable question -- does anybody else have a pretty severe refractory period? If so, have...

I am on my 4th week of TRT. My testosterone was at 265 from a GP lab. Started at 150, 50 3/week. I was having high anxiety on injection day so this week I started 30 EOD. My anxiety and depression is worse than when I started. I am now second guessing using TRT. Should I continue and get labs in...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246784/ "Patients with thyroid disorders are more prone to develop depressive symptoms and conversely depression may be accompanied by various subtle thyroid abnormalities. Traditionally, the most commonly documented abnormalities are elevated T4...

I found that tramadol has a profound effect on my mood. It works by increasing serotonin, norepinephrine as well as working on one type of opioid receptor. Does anybody know of a similar AD?

This happened years ago and again in the last couple of weeks, so may be helpful for some. Various times in my life I have had depression and even after getting hormones tuned up there has been some nagging mild depression that creeps up. My T4 and T3 levels look good, but my TSH has sometimes...

I started TRT 5 weeks ago on 24mg/day subcutaneous injections of Test C (168mg/week). My doc put me on a relatively high dose because my SHBG is very high (maybe 2-3 standard deviations out of range), so much so that despite having naturally high TT levels, my FT was in the dumpster all the way...

I've been on TRT for almost 5 weeks (started the 5th week last monday). I didn't feel much during the first 3 weeks, but at the beginning of the 4th week I started feeling much better. Very focused and clear of mind in a way I'd never experienced before. I've had brain fog my entire life and...

Hey folks, I’ve been on 100mg Test-C 1x/wk for 4 weeks now. For the first 2-3 weeks I was feeling great overall, sense of wellbeing was way up, energetic, more motivated in the gym... just really doing well. The last couple of days have been... not that. I take my Test-C Thursday evening or...

At age 33, After years of depression, anxiety, fatigue, weight gain, sleep problems, ed, etc. I convinced my doctor to test my hormones. I was specifically interested in my Cortisol levels due to prolonged profound amounts of physical anxiety. The results of what he tested were; Total...

Taking my e2 from 72 to 11 and switching to Ed injections has done wonders for my anxiety panic attacks, I no longer feel anxious or emotional! I still have a dead sex drive? should I keep increasing my dose to see where I feel best at(been on this protocol for almost 6 weeks) I wanna see how...

The doctor put me on .5 mg of armidex Ed and my e2 went from 72 to 11 on a sensitive test! Range (8-28) my sex drive is still zero! I’m on daily prop injections of 15 mg Ed! someone recommended raising the dose to 175 mg should I?

PARTICIPATION NEEDED! Of those EM members that have taken nandrolone or are currently taking nandrolone alongside their TRT, we are conducting a small ExcelMale study to help determine the effect that nandrolone has on Total Testosterone, E2, Prolactin, SHBG, free T, and DHT while taking TRT...

I am really fed up with life! I haven’t masturbated in almost 12 months! My libido is non existence my brain is foggy my dick is numb!my anxiety is that of a womanI keep reading about how some people never get there sex drive back on trt! It’s over for me! I’ve taking three doses of .5 armidex...