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  1. L

    Does TRT increase tendonitis?

    I suppose science doesn't have a definitive answer. I was told this by Defy Clinic which many here are familiar with. I did notice when I allowed my estradiol to increase a little the tendinitis went away for the most part.
  2. L

    Does TRT increase tendonitis?

    I've been told that if one reduces their estradiol too low that can cause tendinitis.
  3. L

    TRT Accelerates Artery Plaque Buildup

    I was surprised too because I had always read that TRT protected against heart disease. This was published in the Journal of the American Medical Association. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465430/
  4. L

    TRT Accelerates Artery Plaque Buildup

    I read this article today that is concerning. https://www.cardiosmart.org/news/2017/3/testosterone-treatment-accelerates-artery-plaque-buildup
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    Ibutamoren Mesylate Results

    Has anyone used Ibutamoren Mesylate and if so what was your experience with it?
  6. L

    Testosterone/Estradiol Ratio

    https://onlinelibrary.wiley.com/doi/full/10.1111/acel.13328?fbclid=IwAR3CmxYEvhjvasXU7DvbmmH-aEHldSuh0SNzoyDxcu1lv70jJNK-nr9Dfgk
  7. L

    Testosterone/Estradiol Ratio

    I've been taking .5 mg of anastrozole once a week. Recently I've reduced that to .25 mg once a week.
  8. L

    Testosterone/Estradiol Ratio

    I found this concerning Estradiol. When researchers monitored the estrogen levels of 501 men with chronic heart failure, men with estradiol (the most "potent" form of estrogen) in the normal range (between 21.80 pg/ml and 30.11 pg/ml) had the fewest deaths during a three-year period. Men with...
  9. L

    Testosterone/Estradiol Ratio

    Thank you for your reply! From your formula it sounds like I'm in range with a ratio of 26. I am going to cut back slightly on the amount of testosterone since the amount of .31 ml twice a week has given a level of 845.
  10. L

    Testosterone Estradiol Ratio

    I've been on anastrozole for 11 years. I believe since I started, science has evolved and lowering estradiol down into the 25 pg/mL range is no longer desirable as I have been told to do by my doctor all these years. Recently I've read more and more that estradiol should not be that low in men...
  11. L

    Ratio of Testosterone and Estradiol

    I attempted to post this earlier but it isn't appearing so I'm trying again. I've been on anastrozole for 11 years. I believe since I started, science has evolved and lowering estradiol down into the 25 pg/mL range is no longer desirable as I have been told to do by my doctor all these years...
  12. L

    Testosterone/Estradiol Ratio

    I've been on anastrozole for 11 years. I believe since I started, science has evolved and lowering estradiol down into the 25 pg/mL range is no longer desirable as I have been told to do by my doctor all these years. Recently I've read more and more that estradiol should not be that low in...
  13. L

    Testosterone and HDL

    Really good info here! Thank you. This is something I need to seriously think about. I think I'll also have a chat with my doc about this.
  14. L

    Testosterone and HDL

    Does ratio play a role here? To determine the ratio the total cholesterol is divided by the HDL. In my case 143 divided by 39 gives a ratio of 3.6. According to the American Heart Association, you should aim to keep your ratio below 5, with the ideal cholesterol ratio being 3.5
  15. L

    Testosterone and HDL

    Interesting and scary at the same time considering my doctor has had me on anastrozole for the past 11 years to lower estradiol. Is there new science since then? I thought he put me on it because testosterone converts to estradiol which can have negative effects. Most on this thread have...
  16. L

    Testosterone and HDL

    Thanks for the information. Since I'm already on the high end of normal for estradiol, reducing anastrozole would most likely put me out of range to above normal. There are issues with high estradiol as well.
  17. L

    Testosterone and HDL

    Very good info! I'll be busy reading this. Is .31 ml of testosterone Monday and Thursday along with .5 mg of anastozole too much? Would those amounts be lowering my HDL? I'm at the high end of normal now for estradiol at 32.2.
  18. L

    Testosterone (or Anastrozole?) Decreased my HDL: What Can I Do?

    Great info! I'll be busy reading it. Do you feel .31 ml of testosterone Monday and Thursday and .5 mg of anastrozole once a week is too much? Could this be causing my low HDL? If so, what amount of each should I take to increase my HDL? My estradiol is 32.2 which is near the high end of normal.
  19. L

    Testosterone and HDL

    My last bloodwork shows a testosterone level of 845 ng/dL injecting .31 cc Monday and Thursday. My estradiol was 32.2 pg/mL with .5 mg of anastrozole once a week. I inject .5 ml of HCG twice a week so my balls don't shrink. My current lipid panel is Total cholesterol 143, Triglycerides 62, HDL...
  20. L

    Testosterone and HDL

    Thanks for that great info! I take .5 mg once a week now and I'm at the high end of normal for estradiol at 32.2 pg/mL. I know you are correct about low estradiol lowering bone density but I'm worried if I stop anastrozole and my estradiol increases out of the normal range I run the risk of...
  21. L

    Testosterone and HDL

    Excellent! Thank you.
  22. L

    Testosterone and HDL

    To my original question, any suggestions out there to raise HDL outside of what I'm already doing? Do others out there on TRT also have low HDL?
  23. L

    Testosterone and HDL

    Which could be one reason women have a higher life expectancy than men.
  24. L

    Testosterone and HDL

    Gotcha. I take .5mg of Anastrozole once a week.
  25. L

    Testosterone and HDL

    Thanks for your reply. I administer as instructed by my doctor Monday and Thursday .31 cc by intramuscular injection. I'm a pescatarian with my diet primarily plant based except wild salmon a couple times a week. I work out five days a week. I don't use any performance enhancing drugs. I'm...
  26. L

    Testosterone and HDL

    I have been on Testosterone, HCG and Anastrozole since I was 48. I will be 60 in two months. Can testosterone replacement therapy continue into the later years in life? I monitor all my important bloodwork every six months and everything is ok except my HDL cholesterol. I feel much better...
  27. L

    Huperzine A

    Can anyone provide feedback with your experience with Huperzine A? I've read it has been used successfully to treat delayed orgasm.
  28. L

    Ibutamoren Mesylate

    Hello, Can anyone provide any feedback on your experience with Ibutamoren Mesylate? Safety, results? What it is primarily used for? Thanks, Larry
  29. L

    Penis sensitivity issue

    Great post! I have no issue with ED but occasionally I have an issue reaching orgasm as well. I associated it with age. What is the cream mentioned above to rub on the nuts and dick? I'm on .30 ml of testosterone twice a week and .5 mg of anastorzole once per week. I also inject .50 cc of...
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