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Just a quick status update. Been on the cream for about 5 weeks now. Definitely feel much more stable and have noticed a significant improvement in libido and consistency of morning erections. I’ll have labs done in another couple of weeks but I’m guessing my test levels are a bit lower on the...

Very interesting! I’m trying hard to completely ignore e2 going forward and just focus on optimizing free t.

E2 was 43 at these labs which is consistent with my previous few labs. No AI for a couple of months and never any HCG. These labs were probably peak (if there is one on EOD) bc they were 24 hours post injection. Yeah if this doesn’t work I’m flying to TN to go see Dr. Nichols. I found this...

2 pumps twice daily of 200mg/ml applied to the scrotum. They did start me on 50mg DHEA but that’s it. Too early to tell much, it’s actually only been 5 days. I noticed a slight bump in libido but otherwise don’t feel much different yet. I was actually beginning to feel a little better on...

Just last week I switched over to using compounded scrotal cream and using a new clinic where they are trained using Dr. Rouzier’s methods. The plan is to optimize free t (probably in the 30-40 range I was told) and then give it some time and see how things go. I’ll provide updates along the way.

I have almost identical labs to you and have had a very similar experience in that I’ve felt like I need an AI but am also very sensitive to them. My total t 1100-1200, free 17-21 and SHBG 50-70, sensitive e2 41 without AI. I have always assumed my symptoms were related to e2 since everything...

Do you still like the prop? I’ve read some of your other posts and I know you’ve been at this for a while. Was it you that at some point moved to a very low dose of cyp (like 60mg 1xweek)?

Agreed, I’m 41 with 4 kids and have no expectation of being always-on:). I’m trying to avoid prolonged periods of low/no libido.

Sorry I’m sure I worded that statement poorly. I was referring to the study link that Nelson posted “high estrodial boosts libido in men on testosterone replacement therapy.” I’ve read that study and others that suggest this but I completely agree with you that studies are based on averages and...

2 months ago I switched from an E3.5 protocol to EOD and removed the AI. the labs above reflect that change. After 2 months of just feeling of low libido I decided to try the AI again (.125mg 1x per week). I did notice a slight improvement the first week but after the second dose I saw a big...

This is what always has we wondering if I could figure out how I’m not sure if the reason it’s not sustainable is that I haven’t found the right dose/frequency to maintain the ideal e2 or if it’s just temporary and the effect would fade regardless...and as Cataceous mentioned that just making...

Probably about the same as the year or two prior to TRT. It was great until probably my mid 30’s. Things went down hill after our fourth child was born and I had a vasectomy.

I don’t disagree at all. However after nearly two years on TRT the only times I’ve had a decent libido is when my e2 was in that 18-30 range after taking an AI. I’ve just never been able to sustain it for more than a couple of weeks at a time. So is it worth trying to manage e2 in that range or...

General question about libido and E2. A few times I have dropped my e2 into the 18 range using .25mg anatrazole once per week. I feel kind of down for 2-3 days after taking it and then feel amazing (great libido and mood) for the next 2 weeks or so. Last time this happened I ran labs and e2 was...

Definitely appreciate any advice you can give. After going without an AI for the past seven weeks I think I just do better with it. I know it’s a hot topic i know it’s a hot topic and I would prefer not to take an AI but after seven weeks without it seems like I just need it to feel good. Going...

It's been running at 70 but I actually just got my new results today and it dropped from 70 to 52. My thyroid levels dropped some too which is probably why shbg came down. Haven't spoke with my doc yet you see if he'll be upping the thyroid dose. Free t3 3.2 (2-4.4) was at 4.6 last labs Free...

Took .125mg of anastrozole and felt noticeably better within 24 hours. I just don't understand why I'm so intolerant to e2. I know my levels at 41 aren't what most would consider high. I also know there are studies that show higher e2=better libido but that just doesn't seem to be the case with me.

Gotcha, thanks Vince. In your opinion would you achieve lower e through a dose reduction or by going back to using an AI? It definitely worked but was a bit of a rollercoaster. I would take .25mg every 1-2 weeks and it would generally drop e a bit too low at first, then after a few days I would...

Not sure I completely understand what you mean by there’s nothing wrong with this? Not sure if it helps but when I was taking the AI there would be periods of 7-10 days when I felt amazing but just couldn’t keep it consistently. That’s why I tried to get away from the AI and moved to a more...

No DHEA or HCG

Just received my updated lab results after switching from 50 mg e3.5 days to 28 mg EOD. The hope was that more frequent injections would allow me to ditch the AI. Last dose of AI was .25mg on 3/31. Overall I would say this was a positive move but libido still isn't great. I'm now debating on...

Well I guess I’ll give this a try first and if it doesn’t work I’ll probably try lowering the dose like you did.

This is so interesting. I’ve been on trt for about 18 months trying to get dialed in. I started at 100mg/wk and haven’t really deviated much other than to try different frequency. My SHGB is 70 so total is around 1000 but free is more like 13-14. I never know if I should increase my dose to...

Thanks brother! These are very similar to my labs except my free t is 13.7. I want to try raising that level but without elevating e2 any further. Hoping the switch to mwf will help. I’m only using 50mg e3.5 days though.

Do you mind me asking where your total and free t generally runs?

That’s great! This gives me hope

Wow! Even with a higher weekly dose your e2 dropped from 75 to 30 by increasing frequency to MWF?

I know this is an old thread but I’m in a very similar boat as you with shbg of 70 and injecting e3.5 days. When you went to MWF did you keep your weekly dose the same or reduce it some? I’m contemplating the same move. Thought I would keep my dose the same for now so that I’m not changing too...

That’s great! Trying to convince my dr to let me try more frequent injections to avoid the AI. My shbg is 70 though so I’m not sure if it will work for me but I’m super sensitive to high e2 so it’s worth a try.

Hey man I’m curious about the more frequent injection schedule. Do you mind if I ask what your shbg is and did e2 drop like you expected ?