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I have some Preg capsule at home from Empower, BUD was 05-2023. I'm wondering if potency is still ok or it has been lost substantially, what do you guys think? toss it?

What Preg product are you using right now?

an update on my Hikma Test E trial vs Test CYP from empower. Levels are about the same, a bit less on the Hikma, Testosterone speaking I feel the same, I believe my head feels a bit more clear/natural on the Hikma. I think it is a good idea trying not to inject benzyl benzoate, some negative...

Not much of my intellect, really. You are bringing up good points. Though, oral steroids like DHEA and Pregnenolone, when going through the first pass metabolism get converted into different metabolites, I wouldn’t be surprised if scrotal application of the same steroids would produce a...

I should have mentioned to read the first post on the thread if interested, Hopefully that won’t be too gibberish for your level of intellect.

I'm not sure this has ever discussed here, but I found some very interesting data posted and commented by Georgi Dinkov AKA Haidut on the RayPeat forum, how applying Pregnenolone and DHEA (in DSMO) on the scrotum, can raise serum androgens like T DHT and Androsterone, this because directly...

I believe if someone is not using huge amount of test for prolonged time, I think probably there is not much to be concerned about the 5-ar. Lower levels of Progesteonre/Pregnenolone can be an issue for some

I don’t have the side effects I was experiencing with the injectable. This, as soon as I take it, it really feels calming and soon after when I go to bed I really lay down very still in bed, it is the first Pro I’m using that help me to get to sleep. Some good and bad side effects during the...

I don’t think so. Prog in vitamin E, especially when applied to the gums, will bypass first pass in the liver, like an injection. Pro itself has a very short half life in the blood though, but I heard Georgi Dinkov and Mercola saying that because Vit E has about 44hr half life, Pro when...

Quick update on the Progesterone dissolved in Vitamin E trial. two weeks after applying a drop (3mg) on my gums, it did not raise my Progesterone serum. However, I do feel it.

@Jim Marlowe have you ever tried the StressNon from Idealabs, the Pregnenolone dissolved in DMSO?

and here Cataceous comes as usual with some unbiased, fair and articulate comment backed up with actual science, I much appreciate you. To add to your comment, even while on ketosis, the brain and some other tissues, still require some glucose. In fact, I would think ketones as brain glucose...

it sounds like you have some solid biology here to argue with Ray Peat, too bad he is not longer with us.

What were the vitamin E dosages you recall he was recommending? As far as thyroid, I don’t think he ever recommended high doses of thyroid hormone. He based his thyroid work on Broda Barnes, who would pay attention to body temperature, heart rate and paid attention to TSH, which I do not think...

O I found in his work some "little personal discoveries" I found by digging in the medical literature my self, even before even stumbling into his work. It made me to connect some dots about health, that Peat put together many years ago already. Example of his work the importance of burning...

I have been doing the same since Monday, after about 30/45min I feel super relaxed. Some people also put the drops on the tongue then massage into the gums. I’m starting to think this is really the best way to get Progesterone in, I’ll do some labs in a week or so

I saw this video before. If I had learned about Ray Peat earlier, I would have probably saved allot of time. But when years ago I was exposed to his work, I thought he was a lunatic!

@Jim Marlowe how do you apply your drop of Progesterone on the gums? do you use just a finger and massage it in?

One day I swear I will read all.

currently comparing these two products: https://healthnatura.com/simply-progesterone-1-08-oz/ https://shop.forefronthealth.com/collections/all/products/molecular-progesterone-supplement

@Jim Marlowe have you ever checked Progesterone levels while on the 3mg applied to the gums?

Did you take this in the am or before bed?

Thanks for attaching this paper, good read. The only thing I may not agree with Mercola is the dosing for males, 25/30mg in a delivery method that by pass the liver is wow. Probably 1-3mg daily for a men would be more physiological, unless Pro is used pharmacologically short term. It took me...

this is true, in fact Progesterone can lower ACTH, which I would think Pro would more like reduce the stress response. However, Pro can also feed the pathways and increase cortisol. Individual variations, and possibly the mechanism is dose dependent as well, with little Pro "helping" to produce...

it just doesn't feel right, it feels like years ago when my E2 was uncontrolled, minus the erection quality benefit, plus feeling wired and like I'm on something. Just the opposite of what Pro is suppose to do, and the opposite of Pro is Estrogen, which is excitatory. I have switched to IM...

that is a good point, hypothyroidism people can have same issue with Progesterone

that is so interesting, I just increased the dose since Thursday from 1mg to 1,5mg and switched to abdomen, and I feel crazy again, erections and wild sex thoughts, I would say overly exited and feeling wired, which is just the opposite of Progesterone. I just think I may not doing well...

@FunkOdyssey where did you inject your Pro, and for how long you did you try it? It is interesting comparing my response to yours, typically you would expect your response from Pro. Was your Pro suspended in sesame oil as well?

I have been reading for the past several months the work of Ray Peat. He studied Progesterone and Estrogen extensively since the 70"s I believe. He understood the importance of Progesterone, and figured out that the best route of administration is micronized Pro dissolved in Vitamin E...

Hi Vince, I have been using the injectable since November. I'm sure it is not placebo, the benefits and sides are noticeable and dose dependent

Progesterone scrotal