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I have the same background re Accutane as a teen. I also try to keep DHT high in order to get the benefits I receive from TRT - which for me, is mainly erectile function. Testosterone has made a significant difference in this regard. The rub is that I have to run fairly high levels to get DHT...

I’ve settled on EOD injections. Generally between 34mg EOD (119/wk) to 38mg EOD (133/wk). Last labs were from 38mg EOD (trough before injection): SHBG: 16 TT: 875 TruT FT: 31.5 E2 (LC/MS): 72 This was a good protocol for me in terms of symptom resolution - which is something that sometimes...

Good topic and I’m glad that Cataceous chimed in. I’m also a low SHBG guy (16) that does better at higher levels. It always seems like toeing a thin line though - if my levels aren’t at a certain threshold, it seems like I lose the benefits of TRT. However, just a hair past that threshold I...

When you switched from TC to TE, did you change your total weekly dose?

Great information - thank you for sharing.

I appreciate your input here and I hope that you will stick around. I’m certain I’m not the only one. I also understand your reaction/how you feel about the tone used in replies to your post - in this case, I’m certain that you’re not the only one.

How would you say taking 25mg EOD would compare with taking 12.5mg daily? My primary goals would be improved sleep and tendon pain relief. Also, thanks for the great information you provided in this thread.

5gr 2x/day? For 10gr total per day? I ask because the “high strength” tablets I have are horse pills and are only 1200mg each.

You will not have any issues traveling with syringes, etc. Done it countless times. TSA sees syringes all day long. Diabetics, etc.

The only time I've experienced the snare drum tight scrotum thing was when I was using HCG. Been off HCG for years now, haven't experienced it since.

Sleep issues are not uncommon among guys on TRT, particularly at higher TT/FT levels, and I’m not sure that it’s accurate to blame estradiol in isolation. More likely due to disruption of other downstream hormones, neurotransmitters, etc.

I notice that whenever I make a change to my protocol, I often experience a short-term boost in libido/EQ.

Similar experiences here. Though I did notice that it really helped with chronic joint issues. Also, never tried lower dosages…I’ve read that even 50mg/wk can be effective for joints.

Decreased semen volume and orgasm intensity are not uncommon among guys on TRT.

Sounds like you’re taking too much - many guys complain that they don’t feel well at high levels (and with a trough of 1100 on weekly injections, your peak is likely very high. If libido is the main thing you’re seeking to change (and you’re sick of needles), consider scrotal testosterone...

Assuming TT/FT levels are roughly equal in both cases, would there be any difference between cream and injections in terms of body composition/muscle building?

I’m interested in hearing more about this. Does @Cataceous have insights?

For those of you mentioning subq lumps, PIP, etc: I find that volumes of about .35ml are about the max for me for subq. That is for subq in the VG area. Anything more and I also get lumps. That volume would be far less in abdominal subq. On that note I avoid abdominal subq - I know it works...

1. What is your age? Early 40s 2. How long have you been on TRT? 4 yrs 3. What's your current protocol? 70mg TC E3.5D (140mg/week) 4. How is your libido/desire for sex? Either rate out of 10, or describe in your own words. 10 Libido was high before TRT and TRT as further increased it. 5...

Appreciate you sharing what works for you and glad to hear you're doing well. Please keep us updated.

http://www.bioscience.org/2018/v10e/af/825/2.htm

Where was E2 when it was through the roof? Please post labs and ranges.

To answer your question more directly - if you choose to go off TRT, it seems that simply stopping everything, including hcg, is the simplest solution and perhaps the fastest route to a recovered HPTA.

To be clear, I never had libido issues before TRT. However, if anything TRT has ramped it up even more to the point that it might be too much lol. The reason I bring this up is because I sometimes think TRT is just a part of the puzzle and if something was broken before TRT, TRT alone might not...

Yes, that is common. On your scrotum, not your penis. Also, ask your doc to prescribe you 5mg daily Tadalafil too. In fact, I would not take no for an answer on this...not that they’d have any reason to say no.

Been a while since I’ve gotten this product from them. Last time they were capsules. Just received some and they’re little round light green tablets with a split mark in the middle. That sound right? I can call in the morning but had planned on taking one tonight.

I don’t have an answer for you, but I have also experienced this. I asked about it in another forum and the responses seened to be split between those that thought it was due to high E2/water retention vs high HCT/circulation. Interesting to note that the AI had an almost immediate effect for...

There was a member here a few years back who was convinced of that. In my case, it seems very likely that it had something to do with HCG but I can't necessarily blame it on E2. Recently my E2 got higher than it's ever been (no HCG) and I did not have that issue.

Mine hung very high and very tight only WITH hcg. Without hcg, they’re smaller than normal but definitely not almonds and I no longer have cold water balls lol. Been off hcg for years btw.

IIRC, Nelson was applying all 4 in the morning - I believe he has now moved to 3 in the morning. I can help fill in some of the other blanks here from my experience if that is helpful. Regarding hassle - yes, I did find that the cream was generally more of a hassle than injections. Even daily...

Re SHBG: My personal experience has been that SHBG levels, like side effects, are somewhat dose dependent. For me, higher overall dose combined with more frequent injections lowers my SHBG. Point being, for me, SHBG is somewhat fluid so I cannot accurately answer your question in any way that...