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I think it could make sense to take it at night for the reasons you stated, maybe, who knows, but I have not found anything in that regard, and in almost every research paper I've read when the time of injection is specified it occurs between 7:00 am to 10:00 am I have also read about vitamin E...

Couldn't agree more. I've searched as more as I could and cannot find any serious references to binding to ER receptors outside HP, and I would definitely feel more comfortable if I knew what happens as that would help me predict potential side effects, and explain why in some people, even...

There are countless anecdotes, scientific research, etc, stating clomid is safe an effective in some cases to raise testosterone. As with any medications, it may cause side effects in some people. I've never been on clomid but I have been on enclomiphene for more than 6 months. Testosterone...

@JmarkH This is intriguing. I checked it out and it seems to be high dose of vitamin B6. At least according to one product on Amazon, "...P-5-P contains a potent 25 mg of vitamin B6 (1,471% Daily Value) in the active form of P-5-P (pyridoxal 5’-phosphate)" Do you have any experience with it...

@Systemlord I've seen you've mentioned this several times related to both clomid and Enclomiphene. Would you be so kind as to provide any research or reference stating this? I have looked for all the receptors enclomiphene binds to and I can't find any references other than binding to ER...

I understand the "...sense of a coma. I was awake/asleep at the same time..." as I experience exactly the same thing. Currently on HCG 300 IU M/W/F/S + 12.5mg Enclomiphene on the same schedule. The sense of being awake/asleep correlates with the usage of HCG but I can't say for sure that's the...

Interesting, I was not aware of this. Since you tried all 3 (clomid, Enclomiphene and Toremifene) how would rate their differences, similarity and effectiveness. It seems from your comments that Toremifene was able to increase libido, something usually enclomiphene fails to do. In what sense...

Anybody has any experience with Alfuzosin? It's another alpha blocker with less selectivity for the alpha 2 receptor in the prostate but does not cause anejaculation common in tamsulosin. Anybody has any anecdotes in how it affects morning erection, EQ, and LUTS?

Obviously I do not recommend a pariah forward, but a path forward instead (darn autocorrect) :)

@Zipty636, Welcome to the forum. Based on my personal experience, which may be different from yours, enclomiphene citrate 12.5 mg Every Day (from Empower) for 6 months made me feel better from the psychological point of view, more optimistic, less explosive, less anger, less "laziness". With...

Good point. Nothing's ever as simple as we'd like it to be.

Good point, it will only work if you're secondary AND your pituitary is still able to produce LH. If for whatever reason your pituitary is toast, blocking the negative feedback loop is not going to accomplish much. In that case, HCG might work, but if the pituitary still responds AND your...

I was on enclomiphene citrate for 6 months and my Total T went from 300 to 1183, E2 did not rise much (33 from 27). I felt well "in general" particularly my mood, but other symptoms like libido, did not improve much. I'm now following @JmarkH protocol described above. I have not done tests yet...

I'll be interested in the answer as well, as I'm HCG mono as well and I'm not sure about the dosage going forward,

Guys, as promised, this is an update after 3 months of HCG mono-therapy after trying Enclomiphene for 6 months Unfortunately, I do not have full labs in every instance, my previous andrologist did not order them, and my new one orders a few, and I don't make enough money to get them regularly...

I'm getting Pregnyl from Optum Specialty Pharmacy @ $118 (free shipping). It's a 10,000 units vial. Empower still sells Enclomiphene albeit a bit more expensive. Tomorrow I'll start a protocol similar to @JmarkH, just 12.5mg of Enclomiphene instead of 50, let's see how it goes. HCG alone never...

Thank you so much JmarkH, it seems you're doing really good. My numbers are also good, bur symptoms-wise I'm not seeing much improvement (libido, sensibility, etc). I'll discuss with my doctor to try your protocol and see how it goes. Much appreciated. A.N

JmarkH I see from your signature that yo are taking: - HCG 250 UI 4 times per week - Enclomiohene 50 mg 4 times per week Questions: - Are you still happy with the results of your protocol? - If you don't mind, how old are you (simply to see if I can extrapolate your results to me) - Do you...

Keep in mind I'm 60 years old. I'm doing hCG now, if I don't get much success. I'll try combining enclomiphene. My concerned is that enclomiphene has been banned , so where would I source it? Clomid has bad reputation in some circles due to a supposed estrogenic effect.

Nope. I might have put on some muscle, since I started to lift again, but I would say the effect was not noticeable in any area, just in the labs.

Correcting myself. Optum's Pregnyl is 118.90, A+ Pharmacy carries Pregnyl too for 187.50

Yep. I'm currently ordering from Optum. They are carrying Pregnyl for $188.75 I think. Thanks for the info.

Steve 78, I think you got it right. it has not been discontinued, but backordered while the manufacturer fights some gray-market issues (as I understand it). If you don't mid me asking, where did you get it? I'll be willing to try Pregnyl given everybody says is very effective. How much did...

Interesting... I clicked on the link above and immediately got this warning from my browser

I totally agree with you. Pregnyl seems to have the most consistent results for most people but it's discontinued now. I'm afraid of injecting something like this without the confidence that the product has been manufactured with strict guidelines and it's not contaminated. Greed, for lack of...

well guys, I went to a different andrologist today. He told me that I should not try TRT as my testicles work perfectly well (TT=1183) and I have tried all the tricks in the book, but if hCG worked well, I should try it again and play with the dosage. He said anything from 500 to 3000 IU a week...

Interesting... I wonder what my problem really is or if we understand exactly how everything works. My TT is 1183, FT is a healthy 138, and E2 a good 31, and I have not had morning erections in moths, my sensitivity is really poor, and orgasm is like, quoting a great thinker, "phut rather than...

jacb Nice to meet you. One question, how much improvement T-Cypionate alone does for you? Do you get improved libido, erection, sensitivity? How about mood. One of the things enclomiphene has definitely helped me is making me less moody, and giving me glass-cutting nipples (effect is subsiding...

I agree on on mileage, definitely they've had a good run, and with a new carburetor they still shoot 1100, but you have to push harder on the gas (LH/FSH through the roof) My only hesitation with TRT would be seeing them shrinking, it would break my heart! :cool: (My wife doesn't really care...

Nelson, You've been very helpful. I did not know you could combine both meds in the same shot being water and oil based. Based on the video, I see you use IM instead of SubQ. My shoulders are waaaay less developed than yours :) so I don't know how it would feel, I had thought subQ would work as...

Thank you Nelson! I have already read your book, it's fantastic! and that's the protocol I think I'd like follow. I have an appointment with a new andrologist, as I'm truly disappointed in my first one. I'll try to lead him in that direction, my biggest fear is that when he sees the numbers...