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  1. J

    Help determining proper pregnenolone dosage and frequency

    Their recommendations are interesting that’s for sure. To me, the recommendations make little to no sense based on other published information making reference to the adult adrenal cortex having around 4mg of dhea and 25mg of dheas produced daily. Whether we care is another matter. I’d say 5mg...
  2. J

    Help determining proper pregnenolone dosage and frequency

    https://www.nature.com/articles/pr1981101 Here is an example of oral dheas Now we can figure out a good starting point to consume dheas orally. Also whatever we determine for a dheas dose we would take a % of that amount worth of dhea with it. In physiological dose and ratio.
  3. J

    Help determining proper pregnenolone dosage and frequency

    Larger single doses are also preferentially converted into progesterone, it’s metabolite allopregnenolone and pregnenolone’s sulfated form, pregnenolone sulfate. A human synthesizes between 30-50 mg of pregnenolone daily. So it’s probably the most natural to take 10mg with three meals. Higher...
  4. J

    Nandrolone Experiences

    I think th Nandrolone is quite selective to muscle tissue quite like testosterone. If you rule of 5ar and aromatase nandrolone and testosterone would behave very similarly. This study would play out exactly as we think. These other metabolites are needed to be healthy. Use e2 and dht with...
  5. J

    Progesterone and fertility

    To put it plainly, I’m in no way aware of a mechanism by which it would lower fertility. It’s anti e, anti prolactin, pro dopamine. In the realm of physiological dosing, it doesn’t inhibit anything vital to fertility and seems to be pro many things that benefit fertility. That is my very modest...
  6. J

    Nandrolone Experiences

    This is exactly the primary issue with nandrolone. There is not a sufficient enough e2 for e2 receptor activation in balance with activation of the androgen receptor. For example, one could use exogenous e2 (say 50 mcg of esterfied estradiol valerate or enanthate) with nandrolone and would not...
  7. J

    DHB (1-test cyp) solo, would it be worth doing?

    I don’t remember your full protocol, could you remind us?
  8. J

    How can I make sure I don't start producing? Yes, you read that right...

    They both slightly increase shbg and together increase mine around 33%
  9. J

    Guys on daily SubQ

    8 weeks I believe
  10. J

    How can I make sure I don't start producing? Yes, you read that right...

    Total 800 Ft 16-20 E2 19 Shbg 30-40 depending on if I’m on coffee/cigarettes or not
  11. J

    Guys on daily SubQ

    Emeric also does 5mg per day. He seems to move between cycles of either 5-10 and 20 with an occasional 40
  12. J

    Guys on daily SubQ

    I have followed the 10mg thread on pro muscle. I like how emeric eats a lot of eggs. I started doing this.
  13. J

    How can I make sure I don't start producing? Yes, you read that right...

    How about just inject 2mg of test enanthate daily. My serum levels would be around 200ng/dl if I did this. I still may try to go 4mg daily as an experiment but I am vain and like my pit bull like physic on 8mg daily
  14. J

    Progesterone immunoassay

    I’m curious what this test can pick up on to skew the result? For example the e2 standard assay picks up on crp and inflates the reading.
  15. J

    Help Low E on TRT

    I have used 50mcg daily and it increased my level 25 pg/ml. It brought me from 15 up to 40. 20 mcg is not likely to bring you all the way up to 90-100.
  16. J

    Help Low E on TRT

    Thats great. What is your dose and dose frequency?
  17. J

    low e2 symptoms didnt go away after crash

    Anybody have any estradiol supplementation updates? Still doing it? How are you guys that are doing it feeling?
  18. J

    Any low e2 guys use injectable estradiol?

    I wonder if @Nocalves is doing estradiol valerate still
  19. J

    Any low e2 guys use injectable estradiol?

    I did not notice anything from 50mcg daily estradiol valerate. It brought my e2 from 16 to low 40s. My e2 was normally around 16 while on 5.5 mg test e and 3mg test p daily
  20. J

    Any low e2 guys use injectable estradiol?

    I’m curious if anyone has used injectable estradiol and to what effect? Any changes in sexual health categories?
  21. J

    Quest new test ADH aka Vassopressin

    I’m curious if anyone has monitored this hormone? It is involved with blood pressure among many other functions
  22. J

    Help Low E on TRT

    How is your experiment with estradiol valerate going for you with respect to sexual health?
  23. J

    Newbie confused by prescription, help please

    What was the base/ product you were using?
  24. J

    Newbie confused by prescription, help please

    Is there a rough estimation of the daily peaks and troughs from 2x dosing with 50mg?
  25. J

    Progesterone Dose for Men

    I’m curious as to the exact mechanism. Is it possible that progesterone just competes with other hormones for the 5ar enzyme. More progesterone binding with the enzyme means other androgens have to share more.
  26. J

    Transitioning from subQ test cyp to cream

    What are your current doses of dhea and pregnenolone? What about cream? Have you tried hydrogel base?
  27. J

    A few questions on hormones and erectile dysfunction

    You can do it man! At a minimum mobility work is just healthy AF anyways
  28. J

    B12 and libido

    Yes my homocysteine was 7 so I’m assuming I don’t have methylation issues. I do have higher iron levels and low vitamin d levels
  29. J

    B12 and libido

    I already have high range b12 levels and I took one 1000mcg dose of methylb12 and started to break out next day. That was only symptom and I’m not sure if it is related. Maybe someday I will re examine this
  30. J

    Progesterone Dose for Men

    I did not notice that issue but would only ever use around 1.7 mg per dose topically in an ethanol solution that likely yielded an only 1.25 mg per dose. I would divide dose into 3 times daily spread out as much as possible
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