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Nor-epinephrine decreases during sleep which IIRC has a pro-erectile affect. I and many others have found that PT-141 seems to require sleep to fully "activate" it. Away from sleep, I have found PT-141 to enhance the affect of the viagra-like compounds, but not to be miraculous on on its own...

I have been taking 4mg every two weeks for the last several years. I haven't noticed any strength decrease that would indicate a problem with MPS, and I am stronger overall. Blagosklonny, the last time I heard him interviewed, said that he thought part of the mechanism of action was reduction in...

I would start with DMSO. If that doesn't fix the issue (and not re-injuring the problem is essential) then BPC and or some form of GH secretagouge would be a good next step, as described above. 1-3 mg of BPC at a time injected close to the injury. I've had very good results with BPC patches...

It seems to me that the benefits of tadalafil are sufficient that pretty much everyone (men and women) should be on a low dose past a certain age, whether it is beneficial for HF or not. Trying to figure out everything it benefits seems like a waste of money and time, given that it is about as...

In theory, the combo should be superior for overall health due to the systemic cardio vascular benefits of the Cialis class of drugs, even if the erection results are the same.

I use it (synthagen) but I suspect I use too low of a dose and with too many other variables to really give a good evaluation based on results, but the logic behind it looks reasonable. That said, I would not trust any other brand that I'm aware of. It is apparently faked and diluted quite commonly.

Premature Ejaculation

It's also worth noting that Tren and Primo both apparently have a very pronounced anti-libido/EQ affect in some people. It's especially unfortunate as Tren is one of the very few compounds that help resolve PE for some people, although I think Nandrolone may as well.

I ordered it on 2/16, so not too long ago. Also, I also appreciated your comment that Nandrolone increases synovial fluid and I refferenced you in one of the threads on here about that. That is a possible mechanism for reductions in joint pain that I had not seen before, but I'm far from an...

Welcome!!! I'm eagerly awaiting your book and look forward to your contributions. I am not on the other sites you post on (I am a believer in micro-dosing which seems to generate drama on some forums), but I do read and respect your work. I especially appreciated your reality check on Boldenone.

Since what I referring to is purely speculative and I haven't heard anyone else taking about it, doses and timing have to be guesswork. I don't remember what Dr. Denmeade's intervals are but I seem to recall that his dose was 600mg, although I could be way off. Anyway, if I was going to try the...

In my experience, that is a crazy-high dose. I would start at around 100-300mcg (micrograms) and gradually adjust high, but only if needed. This assumes you are looking for a bump in performance, not a wholesale transformation, in which case other options would be needed.

It sounds like you are on a good path. The issue that jumps out at me is that Vitamin C is really important on many levels and likely at higher doses that most people get. If you take it away from high iron meals I wouldn't expect it to increase iron absorption since it is (as long as it's not...

I'm sorry if you've already mentioned any of the following, but K2, potassium, Vitamin C and low dose aspirin seem like good additions. Moderating stress is also key. Something to raise or prolong nitric oxide is likely a good idea. Sunshine when you can get it has many benefits. If y9our lp(a)...

The decision tree here leads to one thing under all outcomes and that is to get on an anti-cancer protocol. That means things like keeping insulin and blood sugar low, no seed oils, HIIT activity, eliminate visceral fat, periodic fasting, anti-cancer supplements like curcumin, etc. Dr. Nasha...

I agree with this, but with the caveat that you don't want to put yourself into a state of overtraining. I would slightly cut back on something else and, to start, add one BRIEF workout per week of either sled-pushing or sprints on a slightly uphill slope. Total workout time should be no more...

Note that some compounds that increase "muscle size" are basically adding a lot of water retention (e.g. dianabol). There is a mechanism involving calcium IIRC that increases muscle contractile force without increasing the size or number of muscle cells. This used to be the goal of many anabolic...

My first thought was cortisol, but it looks like you've tested that. You might want to check your insulin levels and make sure fasting insulin is under 6 or so. You might also want to work with a holistic doc and test for chronic infections like mold exposure. I know people who have had very...

Also, you might check out the book Adrenal Dominance which talks a lot about anxiety IIRC. I believe the author recommends a low dose of progesterone. Progesterone can be problematic in its own right for some men, however it may be worth looking into to combat anxiety.

Two things...you might try some Lithium and see if that helps with your anxiety. Dr. Sandra Kaufmann thinks IIRC that 20-30mg per day is a reasonable dose, but you would obviously want to start low and adjust up to that only if needed. Also, when I was on clomid only, I could only tolerate a...

The problem with this and similar compounds is they tend to be very temporary. There are fairly few things with enough of an experience base to be run fairly long-term even at lowish doses. Nandrolone is one for those who tolerate it. For RAD, LGD etc. there is a temporary boost, but for what...

In addition, Oxandrolone is one of the few anabolics to be considered Female-friendly, so it is unlikely to have the effect you're looking for, although it seems like there are exceptions to everything so it is worth a try, but if it helps you, I would not think it is because it is related to DHT.

It's not clear why you would change anything if you are in a good place overall. 400mg per week is a hefty dose already.

People dealing with mood issues may want to try supplementing lithium, at least until the N is out of your system. Lithium has other benefits as well.

Good to see a discussion of a very potent promoter of CV health with no mention of cholesterol. Nitric Oxide is a big deal. Also, as Dr Kendrick discusses in his book on heart health (The Clot Thickens), statins (weakly) promote Nitric oxide, so their barely detectable benefit may be due to that...

The times I've tried ND I seemed to get a very subtle version of what USMC describes, however NPP doesn't seem to have any mood negatives.

While not a compounding pharmacy, I have used Peptide Sciences with excellent results. PT-141 and MT-2 (which acts similarly, but with excessive (IMO) tanning affect) seem to be two of the most reliably legit compounds.

I've had some kidney concerns and in general I view the kidneys as a very under-appreciated risk. A few thoughts: - Get a cystatin C test. From everything I've researched, it is one of the best, if not the best, overall test of kidney function. Many of the other tests are very subject to...

I've had lower back issues off and on all my life and one of the first things to try is to lie on you back with a rolled up towel under your lower back (similar to a device called a lumbar extender). Even if this doesn't help, it is simple to try and if you feel muscles relaxing when you do...

I have tried all of these except HGH to try to resolve some nagging joint issues. My next step will likely be HGH and another con I would add is the apparent variation between different HGH sources. All the other things on the list can be tried at fairly low cost from reliable sources, however...

Unfortunately, none of the studies I have seen assessing the risk of Lp(a) have assessed people with high levels who have truly heart-healthy practices such as low fasting insulin, healthy nitric oxide levels, avoidance of seed oils, low inflammation, sensible sun exposure, heart-healthy...