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The problem I see with the SARM category is that there is not the body of evidence, either from studies, analysis or crowd-sourced reports that exists for other AAS. They certainly have an affect, however their risk/reward profile is not as well understood. Perhaps that will start to change...

I had never heard of this but will try the ingredients before my next blood test since my HCT went up for no apparent reason. Lumbrokinase is supposedly much stronger than Nattokinase so I will try that as well. Interestingly (to me) according to Dr. Kendrick ( in his book The Clot Thickens) ACE...

Several ideas...you may want to experiment with DHEA and PT-141 or Melanotan-2 (if you do not get frequent sun exposure) as both of these can enhance libido in some people. Do your research but if you try PT/MT I strongly recommend a starting does of no more than 300 micrograms 3 times per week...

In my observation, it is sufficiently rare for someone to be well-dialed-in that when you are, changing something major is a horrible idea. It's especially horrible since your body is adjusted to your prior protocol and there is no assurance that if you change and then switch back, that you can...

Elevated LH could also be a marker for low T, which is a risk factor for Dementia, so it may not be the LH at all.

Step one for people concerned about dementia is to follow the recommendations in Dr. Bredesen's dementia reversal protocol. Even if a study showed HCG increased risk, if it was done in a population which was trying to give themselves dementia (which is the majority of people in th US) then the...

Antics with semantics in the above... - 4% does not seem "rare" - "Life altering" should be "life destroying" - "persist for years" should likely be "permanent for most of those afflicted with no reliable cure"

As @Type_IIx has covered elsewhere and I think Nelson has referenced in regard to Oxandrolone, the difference between AAS compounds is large and supports what @Cataceous is saying, although with less data on the recently introduced forms. For example there was a study that showed Oxandrolone...

While I don't regret TRT, if I had it to do over again and in situations like yours, I would take a much more staged and focused approach and try to address your issues with less invasive options to start with. Some thoughts: - Consider starting with a SERM like clomid or enclomiphene at a low...

I use and recommend the basic straps for under $10. With those you still get normal grip involvement. Also, I assume you are using an over/under grip w/o the straps, but using only overhand on your lightest sets can give some additional grip work. Bottom line is that your overall deadlift...

In your situation, there is no shame in using straps for higher rep sets. Even if you can maintain your grip I think straps are desirable because it seems to remove a factor which the body senses to be limiting. Don't use the straps for your lighter sets and also add in some farmers walks, power...

Yes, there's a mechanism whereby low salt( likely sodium) triggers a defensive mechanism to retain sodium which has the side effect of raising blood pressure. IIRC it is described in the book.

I had never heard of this but it sounds like a classic example of where correcting a deficiency will correct a problem. Many people are likely deficient in something in salt given how demonized it has been, so correcting that will help those people but will not help others who already get plenty...

To the original question, Meldonium may be an option. I'm not sure TRT at moderate doses is relevant.

This topic is a priority for me right now since I've had a flare-up of some joint tissues for which I'm thinking Exosomes may the next step, and I would want to be in a state of optimal HGH for them to be most effective. I don't know a precise answer and hopefully @Type_IIx will chime in (whose...

There is no magic that makes the prescribed dose a correct dose, especially since correct will change based on circumstances. That is what the wisdom of crowds and the forums like this are for. For example, if the prescribed dose is based on "hard cases" and you are not one of those, then it...

As far as I know. The semi-recent interview with Dave Asprey he did is loaded with great tidbits of info (like bovine testicle powder being a signaling molecule, and why APOB is not necessarily bad) test, and he goes through the issues he had when he was pure carnivore. He's way ahead of most 46...

Paul Saladino has an interesting video on this topic is you search his youtube channel.

IME either of these dosages is way too high to start with, ESPECIALLY for someone also using Trimix where the result could be dangerous. As with anything else it may work for some people and higher doses may be required for "hard cases", however there is no reason to start this high and the bad...

What I have found effective and what I believe Dr. Hertoghe suggests is 100-300mcg (micrograms, or 1/10 to 1/3 of a milligram ) to start with. You can always increase but higher doses seem to create exactly the problem that was reported earlier in this thread...too much in the short run followed...

As has been pointed out in other threads and in my experience, you took a dose of PT-141 that is far too high to start with, so I don't think it's valid to discourage people from trying a reasonable dose (e.g. 100-300mcg) if it's something they might benefit from.

64, on TRT for around 8 years, 90mg T per week plus occasional other things for specific purposes (e.g. pt-141, nandrolone). While I am subject to the increased susceptibility to injury that is generally reported to occur between age 50-65, I've seen nothing magic about any specific age number.

Another factor here is that being dialed in is sufficiently rare that changing anything, especially in pursuit of a theoretical but unknown "improvement" seems very risky. It assumes you can always get back to where you were before and although that is likely true from a numbers perspective, it...

Keep on keeping on! You're a role model. As to your question, I remember seeing that the body actually conserves T as we get older, however there are some people who just do better at higher levels so maybe you're one of them regardless of age. It may also be that if something else is in...

I'm not opposed to nandrolone, however you generally can't optimize across all variables at once. If you want muscle gains, adding carbs and protein is likely necessary and that is what I would try first. What you don't want is visceral fat gain, but adipose tissue is likely no issue at all in...

I am saddened by your situation and I hope that you find a resolution. Note that by restricting yourself to vows that your (former) "wife" has partially renounced, you may also be denying a potential romantic partner the same experience you are missing in your life. There is almost certainly a...

I am a big fan of PT-141 however i have not heard of it for this purpose, and if stimulating the melanocortin system does in fact help with visceral fat loss, I would suspect that it's Melanotan 2 you would want to try. Have you implemented Sean O'Meara's visceral fat loss protocol? Now that you...

Not that it matters for the purposes of this thread, but non-endogenous testosterone can be detected (using Isotopes IIRC) and WADA athletes are tested for it AFAIK. There was a Tour de France winner (before he was disqualified) whose name I am forgetting who tested positive for exogenous T.

Even things that are "bioidentical" can be detected as being from an external (likely lab-generated) source (e.g. testosterone and HGH). I'm not familiar with stanolone but the tests are very sophisticated so that is not a valid reason to consider stanolone to be a meaningfully different...

I think part of the reason metformin has fallen out of favor is chronic use at too high of a dosage. I take it on the occasions where I have a higher-carb meal and won't be active immediately after. That is usually no more than once per week and often less than that. I use either 250 or 500mg...

I would argue that this demographic is more likely to have chronically elevated mTOR for various reasons and, for anti-aging purposes, is more likely to benefit from reduced mTOR. IMO, the optimal dosage is likely unknowable given the hundreds of other variables involved, so for me, it's a...