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N=1 anecdote, it sure did for me.

Thanks. Test names and reference ranges are helpful. Random numbers obviously can be misinterpreted! ;>)

24.3 E2? or Free T? If E2, that is perfect, but it also should be taken in consideration with Testosterone levels. Thanks for the reminder about Canada. I am not sure about Defy and Canada. I am relatively certain they will consult, but probably can't prescribe.

If SubQ works for you, there is NO WORRY ABOUT SCAR TISSUE. I've been on SubQ for about 6 years every other day and the last couple years daily. I use 5/16" 30g insulin syringe and know the sites that produce no reaction on my body. It takes a minute or two to draw the dose, but is painless...

If you guys are able to recreate the wheel, more power to you. We've been doing this for years here. Perhaps just the newness of the environment, but your stories are history repeating itself again. Use telehealth doctors that have a clue and pay out of pocket, or go rogue, get what you can...

Yes, I use it mixed with enanthate. I think straight prop would be too much of a roller coaster for me.

I used Select MDX a couple times 3-5 years ago, was helpful in decision making. Is this MPS2 significantly different/better?

Thanks Madman, it's moot for me.

Medicare does not cover any of them. https://www.goodrx.com/jatenzo Shows $540 to over $1000 a month depending on dose.

OK, lucky man, not applicable to the US. Thanks again.

Thanks, OK, so that's how you got it, how is it paid for?

Looked it up, would break my bank.

Total T is not very helpful, Free T is THE number to focus on. Get the proper lab test, Total T LC/MS/MS with Free T equilibrium dialysis or ultrafiltration, and run your total T SHBG and albumin through the vermuelen calculator. So yes, SHBG is necessary as well. Albumin is from comprehensive...

I am assuming you are referring to some kind of blood donation center criteria, Red Cross is every 56 days, but that is not the whole story. Too many men have posted here about their ferritin being depleted from too many blood donations, even at that approved frequency. If you are donating...

My personal experience, yes at 52-54% my systolic BP increases

I buy enanthate and proprionate through Defy, and mix them myself in sterile vials.

Holy crap, I don't know if it is the long term decrease in dose or something else. My case of high HGB/HCT is potentially multifaceted, but today 16.3/47.7, Hallelujah! I'll ride this out a couple months and see about a small dose increase if it stays down.

You don't "need" that much of a dose. Your total and free T are high, your labs are at "a" trough which means the actual peaks are indeed higher. A potential problem now though is if you decide to reduce your dose, you may feel like shit during the withdrawal for some weeks. Some men do fine...

No Apology necessary, just think you will get more response under a title that is aligned with your question. Cream ineffective raising T enough.

Hmm, deja vu, just posted earlier today. I've been on @Cataceous ' 4:3 enanthate: propionate ratio daily and love it. Personally I would not want the peak/trough swings of just prop. YMMV That said, I would not worry about pausing or phasing, just would switch to the cyp dose.

@madman, I have done labs twice a day several times to satisfy curiosity. While it does not coincide perfectly with ciracadian timing, the enanthate/propionate blend does provide a daily swing. It works for me, and eliminates the water retention and E2 type symptoms I experienced on only T cyp...

Your question is on a pretty unrelated topic thread. Might start a new thread with this question. I know members here have done both morning/evening, and injection/cream combos. I have done both and cream does not work well for me period. I was never fully satisfied with straight T cyp, and was...

Yes ultrafiltration. Not happy about the Vermuelen numbers... Sure not going to reduce dose further! I am calling this the lowest effective dose for my needs. Doing OK, but did feel more super when I was on higher dose. Complicated parsing it all though with the cancer. f I ever pull out of...

Just fine. Though the honeymoon period when I started TRT was like being 18 again, I never had problems even when I was hypogonadal with free T in single digits, and no problems now. Lucky I guess.

Latest on 6.8mg/daily, 3.8/3 ratio of enanthate/proprionate by weight. Previous 7mg/daily 4/3 ratio. HCG 200iu EOD, DHEA 25mg, Pregnenlone 50mg unchanged Total T is fine with me, but Free T took more of hit than I wanted.The ratio looks about on par with the SHBG shift. Of course trying to...

I absolutely believe this too because of my own belief bias! I prefer to call that logic or fact though. ;>)

It is not special case, it is incredibly common. Have your been reading this forum for long? It is constant that men come here with problems from this kind of antiquated protocol. Because something works for you it does not mean that is the norm for others. You are a rare N=1 on one end of the...

Likewise. I am sorry I can’t give simple answers to your questions. There is too much to unpack. I cannot attribute how I feel today compared to how I felt on higher dose during or prior to the cancer and its many severe complications. The symptomatic baseline was wildly shifting for the last...

I am one of the lower dosers on this forum. 6.8mg daily, T cyp/prop blend. I feel well on this. (also DHEA, pregnenlone and HCG). I won't be winning bodybuilding competitions, but I can make modest gains when I try, and I am quite active... in remission from lymphocytic leukemia *(a form of non...

Neither of the arguments for or against use of TRT with prostate cancer are unfailingly correct. It seems pretty well proven that TRT does not CAUSE prostate cancer. Morgentaler debunked this well, and the data supports this However, Androgen Deprivation Therapy (ADT) remains a standard...

1: 3+4 is low grade. 4+3 is more serious. Depending on other factors you may still be good for watch and wait. 2: PIRADS 4 is serious, but may be able to be treated by focal therapy. There are many methods of focal therapy. One of the biggest factors for this is whether the lesion is well...