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“The toxic effects of excessive intracellular calcium (decreased respiration and increased excitation) are opposed by magnesium. Both thyroid and progesterone improve magnesium retention. Estrogen dominance is often associated with magnesium deficiency, which can be an important factor in...

Sounds like the elevated E2 gives you a magnesium deficiency....No need to lower the test dose or take an AI....but you need to feel that for yourself....just create a magnesium spray ....add 7 grams of Magnesium Chloride(minimal food grade) to 100ml water(any but distilled is...

My experience is subjective, no bloodwork on this, but if I take 25mg I become more emotional and have slight pain in my knuckles(my hightened E2 feedback signal). When I reduce it to 12.5mg per day, I feel none of the E2 sides. But again just subjective.

As a trader I used 50-200mg Modafinil with a tiny dose of Propranolol for about 18 months. The reduction in sleep, upregulation of dopamine and other neurotransmitters, etc , high levels of stress and 24/7/365 workschedule I know contributed to my hypogonadism. Sure the cognitive benefits etc...

Also, a body weight increase includes increases in body fat and water retention, not only muscle mass. So your increase in actual muscle mass was probably 50% of what you think, again leading to a quite insignificant increase in metabolic rate by 150 calories/day. You are assuming that I am...

According to this Controversies in Metabolism: In fact, scientific estimation of the metabolic rate of muscle is about 10 to 15 kcal/kg per day, which is approximately 4.5 to 7.0 kcal/lb per day (Elia, 1992). Therefore, the 4.5 lbs of muscle mass would increase the resting metabolic rate by...

Ali Kuoppala has all the goodies on natural optimisation. Amazing resource. Home

Yeah, keep the cardio for short bursts, elevating heart rate and move that thick blood around....

Its not about the amount of energy you use up while working out or moving around. What will give a sustained burn is getting and keeping enough muscle mass that your BMR(Base Metabolic Rate) is high enough to burn that much calories to keep the fat of the midsection, without the need of...

According to this paper , I would start 250IU EOD. If no satisfaction add upwards.

I do not know about the OP, sounds to me all like an advertisement. It feels like he wants to sell me something. Look at his picture, big smile, head slightly tilted backwards and the suit...lol. What kind of person are you to boast about your ¨natural¨ health achievements, on a site where most...

I use 30G, 8mm, .3cc BD I filled them with T suspension or T in Grapeseed or D in Arachid Oil. Different mixtures of injectables all through the same 30G without any issues or loss of product. No pain, no bubbles or depot. Fill them in a minute, inject in 10-15 sec.

I have read on other fora people experiencing something similar relating to NO/pump Vs ester.

In the attached research paper I read that 250IU's EOD is probably a better start then 500IU's. You can always up the dose if results do not give needed satisfaction.

Ask if they want to check ACTH.

Check your adrenals when you are at it......

@Vince only one way to find out...:)

I have been on 2x1000mg a day but I lost my endurance(Kun Khmer/Muay Thai training) and workout capacity/volume. I had no common sides from it, no diarrea etc, but felt physically limited. A strange feeling of being limited by the amount of energy the body had stored or could generate on the...

@DS3 :cool: Thanks for the confirmation....one could expect that the higher binding affinity of especially Proviron and in lesser degree Masteron to SHBG will free up more Test. Which could again be aromatised into E2, etc. (I only know that DHT is giving me a Rock Hard Johnson)

Sure, problem is we expect/assume that science is more objective because of the scientific method but nowadays it is mostly serving the agenda who pays for the research and scientists funding.

And there is something called ¨Confirmation bias¨

The attached study implies not a vasoconstriction but the loss of ability to regulate vasoconstriction through nitric oxide bioavailability and impairs endothelium-dependent vasodilation , which one can assume could create a problem for penis tissue to swell up.

Funny was that straight after I proposed that solution @DS3 He immediately knocked it down with his experience with Proviron giving him a new set of trouble by driving down his estrogen...

LOL you are repeating what I was stating from the study, but I was stating it as in DECA-dick situations or where a body is a bad 5AR converter the DHT can be overwhelmed by DHN and knock the DHT off the AR(comes from one of your posts), so in these cases adding a DHT derivative as I was...

This was in a response to a previous post that DHT derivatives could be a solution or prevention to DECA-Dick as it seems like DHN is binding to the AR and produces vasoconstriction. To counter that and or knock the DHN off the AR or restrict its binding by having higher levels of DHT which...

The study is about binding affinity, thats why I placed it after the statement that DHT has a higher AR binding affinity then DHN. If DHN narrowed the veins in the penis, wouldn’t that result in men having issues getting erections? Huh? I thought this was about DECA-Dick? (Did I post in the...

DHN basically narrows the veins in the penis. As DHT has a higher AR binding affinity then DHN, I will keep my DHT derivatives while adding the Nandrolone. Different binding of testosterone, 19-nortestosterone and their 5 alpha-reduced derivatives to the androgen receptor of the rat seminal...

Again as for this body it is, as from experience adding 12.5mg Mesterelone or now 9mg Drostonelone Enantate a day I feel calmer more centered and at the same time a bit more go getter while being horney.

In this body that would be DHT as it is not a good 5AR converter and to keep the DHN of the AR in the brain and penile tissue.

Full paper: https://sci-hub.tw/10.1002/cpt1973145862

I only got achy knuckles after my 80 days test with Proviron. Achy joints, knuckles and being slightly emotional are my feedback signals to lower my Masteron dose as it indicates lowered E2 for me too. I also use DHEA to up the E2. Libido has never been an issue. I have not started the...