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Until you have the lab results, everything is just guesswork at this point.

Sorry to hear this. If you have a chance to do a search, you will find my previous posts on DVTs/clots. All I can suggest is that you need a complete workup for hypercoagulation (to check for familial thrombophilia) and an RA antibody panel to rule out RA since there is family history. I posted...

Doing a trial of enclomiphene first and running labs every month or so might be the best way to evaluate before giving up and jumping over to TRT. Thoughts?

Any updates on this yet on your end? Regardless of the availability/sourcing issues, my main concern would be whether we can assume that enclomiphene is essentially nothing more than clomiphene minus the zuclomiphene - - or if it will actually produce the subjective benefits comparable to frank...

For those interested, the struggle to find a U.S-based pharma grade supplier is now over. Tailor Made Compounding Pharmacy now offers it and licensed physicians can prescribe it: Box If anyone is already using it, please give us details, specifically, if it is nothing more than clomiphene...

All transdermal deliveries will boost DHT over injectable, however, it appears that transcrotal application raises it even more: https://onlinelibrary.wiley.com/doi/full/10.1111/andr.12357 We need some DHT, but if you're prone to male pattern baldness, this may accelerate it even more.

I have been doing LCHF for the last 10 years and it is not working too well I'd say. Chronically restricting carbs does not seem to be the answer in my case. In fact, it may even be counterproductive. Going over ~75g is likely counterproductive as well unless I increase insulin sensitivity by...

Only problem w/ strict keto is it can crash your thyroid and alter your gut flora if you stay on it longer than 2-3 weeks. I've been doing LCHF/modified keto already (~75g carbs/day) just to keep balanced somewhere in the middle.

One of my major goals for this year is to find ways to effectively recomp (drop bodyfat and retain lean mass or increase) for both wellness and cosmetic. In my case I need to lose ~ 30 lbs total while trying try to retain LBM and get to no more than ~16.5% bf. No small feat for me, especially...

Curious to know if anyone is using Tailor Made. They are one of the few FDA-regulated pharmacies that offer pharma-grade peptides: https://tailormadecompounding.com/about-us/ More from Jay's chat with Ryan@ Tailor Made: http://www.totrevolution.com/why-peptides-are-the-future-o…/

What sign up are you referring to? Androxal trial? I have always been skeptical of online peptide pushers. Did you hear some negative feedback on the liquid? Wondering if the hcl version would work from a trusted US source: Enclomiphene hydrochloride SML0719 citrate: Enclomiphene citrate |...

Did you ever trial enclomiphene?

Specifics as to dosing should be addressed with your endocrinologist.

So I assume you were diagnosed with AGHD as documented by your tests and symptoms? The tough part is getting insurance to cover even with a clear cut case of AGHD, but you probably already knew that. Other question I'm curious to know: have you had a brain MRI to determine if you have ESS (empty...

Just curious - What was the GHST you had done? Glucagon? What is your IGF-1 level? Are you using the Genotropin Miniquicks?

AFAIK, the CAC is a specific CT scan that directly measures any detectable calcium in your coronary arteries. Other than that - CCTA, MRI, PET, angiogram will show visible plaque. Yes, you're right, there are some that feel that removing hardened plaque can be dangerous as it can dislodge and...

My AA is actually low, probably because I consume a ton of n-3s to reduce it, so I don't worry about it. Got bigger fish to fry!

TC/LDL-C that low is just as bad, if not worse, than elevated TC. The pt's CIMT results proves that. Throwing statins in the mix will just make things worse and does NOTHING to directly reduce Lp(a) and, in fact, could increase it. https://www.ncbi.nlm.nih.gov/pubmed/28183512 Better to...

I had my OxLDL level measured and it is elevated! So was hsCRP. So, despite my "perfect" modified keto diet free of any processed sugars or anything processed and tons of anti-inflammatory supplements, I am a victim of inflammation. I also have a long history of Pattern B particles, elevated...

Welcome to the high Lp(a) club, lol! Well, at least you know to take some proactive steps to keep it in check for now until the new drug, AKCEA-APO(a)-LRx, gets final FDA approval (http://www.lipoproteinafoundation.org/) Until then, high-dose niacin and/or tocopherol nicotinate, lysine, vitamin...

Lp-PLa2 is a different marker than Lp(a). When elevated, they are both atherogenic. In response to your second question, I would say that sounds like a conspiracy theory. I had my 23andMe.com test done 6 years ago and have filed probably hundreds of claims since with no issues.

SFAs from CAFO-raised meats and pastured, organic, grassfed meats are like comparing apples to oranges. I've never seen CV studies using the latter, and until I do, I would not take them to heart (no pun intended). I've read both pro and con of dairy fats effect on CVD. Again, never seen a study...

Congrats on a zero score! If you want to proceed with advanced lipid testing I would recommend either the NMR LipoProfile or Quest's Cardio IQ® Advanced Lipid Panel and Inflammation Panel.

Omega 6 PUFAs (corn, safflower, canola, soy oil) are all highly oxidative and inflammatory oils. Omega 3s are also PUFAs, but are supposedly less prone to oxidation/rancidity. SFAs are not prone to any oxidation, second to that are MUFAs. For heart health, I therefore would keep PUFAs (other...

IMO, do the CAC score test for sure to determine if you have any arterial plaque. Costs $100 out of pocket, worth every penny to find out where you stand. If zero, you needn't worry much about your other markers as much.

From everything I've researched, insulin resistance (IR) is the main driver for CVD in general (elevated Lp(a) included) so, unless one has the APOE4 variant, whole food fats (MUFAs and SFAs, and NOT PUFAs) are not the enemy and are beneficial to lipid profiles. According to Dr. William Davis...

Did you measure your Lp(a)?

First off, Lp(a) levels are entirely genetically-determined. Secondly, SFAs have been shown to reduce Lp(a) levels, not increase them: http://atvb.ahajournals.org/content/17/9/1657 https://www.healthcentral.com/article/what-your-doctor-didnt-tell-you-about-lipoproteina...

If you don't mind, PM me your lipidologist's contact info. Am needing an expert in that area - and for thyroid. Thanks.

Are your docs functional medicine docs? Although there are some good ones, I don't consider chiros and naturopaths true docs. The challenge I have is in finding MDs/DOs that know more than I do when it comes to supps, hormones, etc. That is a goal this year.

I already take 3-4g of vitamin C with different forms of iron and STILL have low ferritin. I also checked for internal bleeding and was cleared. Something else is blocking absorption or my iron needs are higher than average, the mystery continues.