Has anyone had any really bad sides with PT-141?

IPRMAN2005 · Apr 4, 2023

Here is my recent experience with PT141. Before I begin, I am 46 y/o, 270lbs and use a 10ml vial of PT141 with 1ml of Bacteriostatic water added. I always use a 100 unit Insulin Syringe and with dosage of PT141 is at 20 units or .2ml of PT141. I hope that made sense

Injected at 5:30am, some nausea, some flushing but OK overall. I have only used this product a few times and it always seems to take about 9hrs to kick in so by 2:30pm I was ready to rock and roll with an erection that seemed to never go down. My wife came home at 4:30 for round 1 and 7:30 for round 2. Still feeling the affects over 24hrs later.

There are some side affects-Headaches and some upset stomach but nothing that really required any additional meds. I think it did make me fell a little tired but not sure yet. Overall I think it was pretty good, but just so weird that it takes so long for it to kick in for me.

DorianGray · Apr 4, 2023

7-8 hour kick in is typical. There is a sweet spot in dosing that will minimize the side effects. Start low and creep up to find it.

You are using a product from an online peptide site rather than a pharmacy?

IPRMAN2005 · Apr 4, 2023

DorianGray said:
7-8 hour kick in is typical. There is a sweet spot in dosing that will minimize the side effects. Start low and creep up to find it.

You are using a product from an online peptide site rather than a pharmacy?

IPRMAN2005 · Apr 4, 2023

DorianGray said:
7-8 hour kick in is typical. There is a sweet spot in dosing that will minimize the side effects. Start low and creep up to find it.

You are using a product from an online peptide site rather than a pharmacy?

Yes, Peptide Sciences. Is this a bad move?

DorianGray · Apr 18, 2023

IPRMAN2005 said:
Yes, Peptide Sciences. Is this a bad move?

Hard to say. Some claim good results, others say they've gotten ineffective product. I have a general mistrust of companies producing pharmaceuticals who are not regulated and accountable.

excelnelg · 2025-04-18T11:12:52-0500

On my second trial of PT 141. First time, all I got was the worst nausea of my life. This time around nausea plus extreme muscle pain. I'm a bit unique in that I have Chronic Fatigue Syndrome and I think that PT 141 just doesn't play nice with me because of it.

Guided_by_Voices · 2025-04-18T12:48:42-0500

excelnelg said:
On my second trial of PT 141. First time, all I got was the worst nausea of my life. This time around nausea plus extreme muscle pain. I'm a bit unique in that I have Chronic Fatigue Syndrome and I think that PT 141 just doesn't play nice with me because of it.

How much did you use? More than 300mcg is unnecessary and a potential problem IME, however it may just not be for you.

WhiteMale · 2025-04-18T12:51:26-0500

My naeusea was very short lived 10-20 seconds. Otherwise its been very sporadic, I've had no physical erections but at one time my mind was consumed with sex that I couldn't think straight like all day long.

VacationMan · 2025-04-18T18:51:40-0500

excelnelg said:
On my second trial of PT 141. First time, all I got was the worst nausea of my life. This time around nausea plus extreme muscle pain. I'm a bit unique in that I have Chronic Fatigue Syndrome and I think that PT 141 just doesn't play nice with me because of it.

There was only one time that I had bad nausea from PT-141, and that was when I injected a larger dose than normal. Usually 1.5 mg is all I need. Doc prescribed up to 2.5 mg and that was too much. At smaller doses, it does take a little longer to kick in and I have a small amount of flushing early on. But when it kicks in, look out - Game on!

excelnelg · 2025-04-19T09:52:59-0500

Guided_by_Voices said:
How much did you use? More than 300mcg is unnecessary and a potential problem IME, however it may just not be for you.

I was well within the normal limits and I very carefully went through a couple weeks trial of starting small and increasing. It's just me and the CFS. It triggers lots of inflammation and pain and gives none of the benefits.