Recent content by Marco N Cognito

Causes for OSA. A collapsed or narrow airway can be caused by numerous different anatomic changes over time or deformities caused by external forces. Just to give you one example, in my case, I had bicuspid extractions and braces as a child. What that does potentially is cause narrowing of the...

Soft plaque volume increased. Have not heard this before. Has anyone measured their CAC score before and after TRT (then again, a CAC test would only show calcified plaque)? Testosterone Treatment and Coronary Artery Plaque Volume in Men With Low Testosterone...

Never as good as I want it, but not on TRT currently. This news adds more fuel to the pro-TRT fire for me though.

https://www.snpedia.com/index.php/Orientation

"Body composition analysis showed that the CC genotype of rs1062033, and the AA genotype of rs700518, had significant increase in total lean and appendicular lean mass compared to CG and GG, and AG and GG, respectively." I won the genetic lottery on this one! I am CC and TT (AA) respectively...

Excerpted from Chris Masterjohn's, PhD newsletter: A preprint* released yesterday by collaborators from the medical schools of Stanford, Columbia, University of Minnesota, UC San Diego, and Taiwan's China Medical School provided the first evidence of the expression of ACE2 in the upper...

supportive: https://www.frontiersin.org/articles/10.3389/fimmu.2018.00336/full...

What about n-3's (i.e. marine lipids)?

Interesting. Thanks. Keep us posted on more results from this protocol. https://www.ncbi.nlm.nih.gov/pubmed/8724115 Have you looked into the new Rx for FH, Nexletol? Less side effects than statins...

ARB Telmisartan effective for those already infected, but what about for prophylaxis??? https://www.ncbi.nlm.nih.gov/pubmed/32356926

UPDATE FROM MEDCRAM:

https://www.reuters.com/article/us-health-conoravirus-blood-pressure-ins/blood-pressure-drugs-are-in-the-crosshairs-of-covid-19-research-idUSKCN2251GQ

https://www.the-scientist.com/news-opinion/blood-pressure-meds-point-the-way-to-possible-covid-19-treatment-67371?fbclid=IwAR1SvNF5rIs12tK2I2HI5A2OqGuQWh7Ps5J4psPfLQcrkw7dmT5FGGfIZck

https://www.cebm.net/covid-19/angiotensin-converting-enzyme-ace-inhibitors-and-angiotensin-receptor-blockers-in-covid-19/

Much of the controversy about the positive or negative effect of ARB/ACEI is based on a time confusion. The positive effect of ACE2 would only occur AFTER the SARS-CoV-2 entered into the target cells. On the opposite, BEFORE its entry, the ACE2 availability may potently increase the number of...