However, you’re using it as an adjunct to TRT. I doubt you’d notice a 10-20% decrease. I use it as HCG mono, in which case such a decrease could lead to a 10-20% decrease in T levels, which could be more noticeable.
This is an awesome thread. Thank you for the updates!
I am on HCG mono myself and would love to try an enclo restart. Your story gives me hope. How do you feel now?
How delicate is reconstituted HCG? I know this question has been answered with respect to HCG powder. And supposedly reconstituted peptides such as GLP-1s and HGH are not as delicate as widely thought.
But is this true for reconstituted HCG?
The serm effect on IGF-1 may not imply anti-estrogenic effect on the liver. Rather the reduction in IGF-1 may result from lower growth hormone levels from anti estrogenic effects at the pituitary. Growth hormone stimulates IGF-1 production.
It’s interesting how people often talk about how we don’t know the long term effects of serm monotherapy, and use this as a reason to justify T monotherapy or T+HCG therapy. But who is to say we know the long term effects of T monotherapy or T+HCG? The kisspeptin research clearly demonstrates...
Thank you both for your replies.
@Cataceous My theory is that the use of Anastrazole may be responsible for the “Clomid effect” with HCG mono. HCG mono protocols often require the use of anastrazole, which may counteract symptomatic relief. People have often reported feeling “low estrogen...
I’ve been on HCG mono for some time now and my labs have recently looked strong.
(On 600iu EOD and .5mg Anastrazole a week, my labs have been T in the low 600s and E2 in the mid/high 30s. My SHBG is about 20.) Prolactin is normal.
While I have slimmed down alot on this protocol, I have been...
From what I’ve read on the forum, it seems like many of Defys starting protocols surpass the upper limit of what might be considered a reasonable high-dose. 140mg a week seems like a commonly described Defy protocol, whereas I would consider 100mg to be a reasonable high-dose.
Thank you @Cataceous for your thoughtful point.
I wonder if one reason testosterone levels have been falling in recent decades is perhaps because it is actually healthier to have slightly below average levels of testosterone. No doubt there are negative factors causing the fall in testosterone...
I’m not sure this point sums it up—if anything it goes against what I was trying to say because they endorse the “high-normal” theory because they claim that 800-950 is generally the best place for testosterone levels.
I agree that a level of 265 (or 365 for that matter) should probably...