I was a patient of Dr Gordon's at one time. I don't mean to be critical of the guy, but my experience with him left a bad taste in my mouth and I have some doubts about the necessity of pregnenolone for the average guy on TRT.
While I like him very much on a personal level, and I don't doubt he is a very intelligent man, I had issues dealing with his rigid protocol and what I feel is a money grab from his patients.
I was on TRT for 4 years before going under his care and had no sort of deficiency in pregnenolone or any of the downstream hormones, but he was insisting I take mega doses of it anyway which left me in pretty bad shape. He sells these supplements through his office at a very marked up price. He also insists on you taking the brands of multivitamin, b complex, and other nutrients that he sells through his office, which alone can total a couple hundred bucks a month.
He also wants all of his patients taking clomid 2-3x per week on TRT which for most men does nothing to restore LH if injectable test is being used, except for usually add unwanted side effects - and as a lot of us know, depression is a very common side effect of Clomid use.
Dr Gordon also, unfortunately, is not up to date with the
sensitive estradiol test and the lab he works with only use the standard assay.
He has one testosterone dosage he uses for all patients and will not adjust it. His office fee for refilling a testosterone prescription, if you don't get the military discount, is $375 - that does not include the price of testosterone itself or shipping.
My new doctor explained to me that while there is a pregenenolone pathway activated by LH, the bulk of it comes from the adrenals anyway which in his practice he has not seen affected by normal TRT programs.
I don't doubt it helps some men, especially those with pre-existing adrenal inefficiencies that require them to need pregnenolone supplementation of some kind.
But its important to remember, just because taking something makes you feel good, doesn't mean that you were actually deficient either! A healthy male might feel good off of a shot of testosterone even without being deficient! There are SO many factors to depression besides pregnenolone.
A lot of the doctors in the TRT world make a lot of money selling these ancillary products, and it is in their best interest to sell them to you when they may not be needed for most guys if their only problem is testosterone related.