madman
Super Moderator
*7:00-13:20 (DHT, estradiol, 5ARIs, AIs)
On this episode of the Dr. Geo podcast, we have a special guest, Dr. Mohit Khera, a renowned urologist and professor in the Scott Department of Urology at Baylor College of Medicine. He holds the F. Brantley Scott Chair in Urology and has extensive experience treating male and female sexual dysfunction, men's health, and hormone replacement therapy.
This captivating episode reveals the intricate relationship between testosterone and the prostate. Throughout the episode, we explore the nature of testosterone, its receptors, and its effects on the body. We also address controversies surrounding testosterone and its relationship to the prostate, including the development of prostate cancer. Join us as we gain insights from Dr. Khera's wealth of knowledge on this fascinating topic.
Chapters
00:00 The Testosterone Link to The Prostate with Mohit Khera, MD [EP 61]
03:20 Why is testosterone even important?
06:29 Low T…treatment. What's that process like?
08:41 Too much testosterone, you can get more dihydrotestosterone
09:03 Higher DHT may increase hair loss
09:07 Why Finasteride is sold
12:52 Is there ever a point that you need Finasteride?
13:23 300 nanograms per deciliter of testosterone..below that number, the insurance company will cover you.
14:29 Exercise doesn't really do anything to testosterone?
15:31 You can measure androgen receptor sensitivity through a blood test
20:31 Lifestyle modification,
21:09 Lose 15% of your body weight…300 nanogram deciliters increase in testosterone.
22:39 Sleep deprived … 15% decline in serum testosterone.
24:16 The ballerina effect.
24:58 Free testosterone
26:54 How do we get free testosterone?
31:07 Should I raise my total just for longevity and health reasons?
32:30 Lupron is a injured deprivation therapy
33:33 Testosterone…PSA will go up almost inevitably
39:01 The majority of prostate cancer is clinically insignificant, meaning that they will die from something else.
39:09 Huge movement of patients now on active surveillance. And they have low grade cancer, low volume cancer
40:49 Testosterone does not increase the risk of prostate cancer.
44:07 Bipolar antigen therapy
45:33 Bipolar and deprivation therapy? Or is it just testosterone?
47:10 The transformer trial
48:57 The study that suggested or concluded that TRT increases the risk of cardiovascular disease? 51:01 How about in men with a history of cardiovascular disease
56:21 So some men can't do the injectables. Orals is a very good alternative
On this episode of the Dr. Geo podcast, we have a special guest, Dr. Mohit Khera, a renowned urologist and professor in the Scott Department of Urology at Baylor College of Medicine. He holds the F. Brantley Scott Chair in Urology and has extensive experience treating male and female sexual dysfunction, men's health, and hormone replacement therapy.
This captivating episode reveals the intricate relationship between testosterone and the prostate. Throughout the episode, we explore the nature of testosterone, its receptors, and its effects on the body. We also address controversies surrounding testosterone and its relationship to the prostate, including the development of prostate cancer. Join us as we gain insights from Dr. Khera's wealth of knowledge on this fascinating topic.
Summary
In this podcast episode, Dr. Geo discusses the link between testosterone and prostate health with Dr. Mohit Khera, an expert in men's health. They cover the importance of testosterone in men, its benefits, and its metabolites' impact on various aspects of health, including energy, libido, muscle mass, and more.Highlights
- Testosterone's significance since 1935 and its effects on men's health.
- Various formulations for testosterone treatment, including injections, patches, pellets, and more.
- Benefits of testosterone therapy improved energy, libido, erections, muscle mass, and reduced depression.
- Importance of estrogen balance and potential risks associated with excessive or inadequate levels.
- DHT (dihydrotestosterone) and its role in hair loss and prostate enlargement (BPH).
- Concerns and potential adverse effects of finasteride, including mental health and sexual function.
- Individual variation in optimal testosterone levels and the concept of receptor sensitivity.
- Influence of exercise on testosterone levels, with different outcomes based on exercise intensity and duration.
Chapters
00:00 The Testosterone Link to The Prostate with Mohit Khera, MD [EP 61]
03:20 Why is testosterone even important?
06:29 Low T…treatment. What's that process like?
08:41 Too much testosterone, you can get more dihydrotestosterone
09:03 Higher DHT may increase hair loss
09:07 Why Finasteride is sold
12:52 Is there ever a point that you need Finasteride?
13:23 300 nanograms per deciliter of testosterone..below that number, the insurance company will cover you.
14:29 Exercise doesn't really do anything to testosterone?
15:31 You can measure androgen receptor sensitivity through a blood test
20:31 Lifestyle modification,
21:09 Lose 15% of your body weight…300 nanogram deciliters increase in testosterone.
22:39 Sleep deprived … 15% decline in serum testosterone.
24:16 The ballerina effect.
24:58 Free testosterone
26:54 How do we get free testosterone?
31:07 Should I raise my total just for longevity and health reasons?
32:30 Lupron is a injured deprivation therapy
33:33 Testosterone…PSA will go up almost inevitably
39:01 The majority of prostate cancer is clinically insignificant, meaning that they will die from something else.
39:09 Huge movement of patients now on active surveillance. And they have low grade cancer, low volume cancer
40:49 Testosterone does not increase the risk of prostate cancer.
44:07 Bipolar antigen therapy
45:33 Bipolar and deprivation therapy? Or is it just testosterone?
47:10 The transformer trial
48:57 The study that suggested or concluded that TRT increases the risk of cardiovascular disease? 51:01 How about in men with a history of cardiovascular disease
56:21 So some men can't do the injectables. Orals is a very good alternative
