Anabolic steroid use, brain health and dependence

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madman

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Anabolic steroid use has been found to have negative effects on brain health, cognitive function, and mental health, particularly in long-term users and those who develop dependence.

Highlights

  • Anabolic steroids can lead to smaller brain volumes, reduced cortical thickness, and structural changes in the brain, impacting cognitive function.
  • Steroid dependence is associated with thinner prefrontal cortex, executive deficits, impaired social cognitive abilities, and personality pathology.
  • High prevalence of steroid use and dependence has been found in patients in treatment for substance use disorders.
  • Long-term steroid use is linked to accelerated brain aging and cognitive decline.
  • Non-dependent users generally do not show significant differences from weightlifting controls on most measures.
 
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