Excel Male Health Forum

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

24,000+ Active Members
33,000+ Discussions
20+ Years Expert Experience

Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel brings over 20 years of clinical research experience, having worked with major pharmaceutical companies and authored definitive guides on testosterone therapy. As founder of DiscountedLabs.com and a recognized expert in men's health advocacy, Nelson ensures every discussion on ExcelMale meets the highest standards of accuracy and usefulness.

Ready to Optimize Your Health?

Join thousands of men who have transformed their lives through evidence-based hormone optimization. Ask questions, share experiences, and learn from experts.

Smoking Cessation's Effects on Male Hormonal Levels
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This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...
Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis
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From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...
Pregnenolone in Men: Help determining proper dosage and frequency
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Wondering what pregnenolone dose and frequency works best for optimizing your hormone balance on TRT? Pregnenolone, the "mother hormone" that serves as a precursor to numerous steroid hormones, requires careful dosing consideration due to its 3-4...
The hormonal regulation of men’s sexual desire, arousal, and penile erection
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Briefing Document: Hormonal Regulation of Male Sexual Desire, Arousal, and Penile Erection Source Rastrelli, G., Antonio, L., Carrier, S., Isidori, A., & Maggi, M. (2025). The hormonal regulation of men’s sexual desire, arousal, and penile...

Anastrozole - Enduring Side Effects 5 Years Later

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Hello all, I’m 28yo male in the US. When I was in my early 20s, I had a residual puffy nipple from puberty. I was very self conscious about this, being pretty deep in weight lifting, and my primary care physician prescribed an anti-estrogen...
Enclomiphene restart - how long?
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38M who has been on TRT + HCG for ~5 years or so. I wanted to see if I could restart production with the help of enclomiphene, as prior to TRT I had a great response to clomid but could not handle the estrogen related sides. I started 12.5mg ED...
Medications that Can Impair Muscle Mass and Strength Gains from Resistance Training
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Introduction Many common medications – both prescription and over-the-counter – can influence the muscle mass and strength gains achievable through resistance exercise. Some drugs impair or blunt muscle hypertrophy and strength development, while...
Prostate-Sparing Focal Therapies (IRE, Cryoablation, TULSA) & Quality of Life
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In this episode, Dr. Geo sits down with Yale’s Dr. Preston Sprenkle to explore cutting-edge organ-sparing treatments—like IRE, cryoablation, and Tulsa Pro—that precisely target cancer while preserving urinary and sexual function. Learn how focal...
Erection Supplements- Do They Work to Improve ED?
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Briefing: Erection Supplements and Erectile Dysfunction (ED) This briefing reviews information from the "Erection Supplements- Do They Work to Improve ED?" discussion on the Excel Male TRT Forum, focusing on the efficacy, safety, and regulatory...
WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT
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Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert...
Erectile Dysfunction Therapies: Testosterone, PD-5 Inhibitors, & Beyond
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Can we do more than prescribe pills to address men’s sexual health complaints? In this episode of the BackTable Urology Podcast, men’s health expert Dr. Mohit Khera from Baylor College of Medicine joins guest host Dr. Amy Pearlman for a deep dive...

What it the purpose of Sex Hormone Binding Globulin (SHBG) ?

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My question might be a basic one, but what is the purpose of Sex Hormone Binding Globulin (SHBG)? In general terms I appreciate that SHBG binds to Total Testosterone (along with Albumin) to give us Free Testosteron. My question is not about...

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