Sleep Duration and Inflammation (CRP) in Adults

[Nelson Vergel]

Sleep Duration and C-Reactive Protein in US Adults.
Richardson MR, et al. South Med J. 2017.

South Med J. 2017 Apr;110(4):314-317. doi: 10.14423/SMJ.0000000000000632

Abstract

OBJECTIVE: To use gender-stratified logistic regression analysis to examine the associations between elevated C-reactive protein (CRP; >3-10 mg/L) and sleep duration.

METHODS: The study sample included male (n = 5033) and female (n = 4917) adult (20 years old and older) participants in the 2007-2010 National Health and Nutrition Examination Survey. Sleep duration was categorized as short (≤6 hours/day), adequate (7-8 hours/day), or long (≥9 hours/day). Logistic regression models were adjusted for age, race, smoking status, physical activity, and waist circumference.

RESULTS: Analysis revealed significantly (P = 0.0151) higher odds of elevated CRP in men reporting ≤6 hours/day of sleep (odds ratio 1.26, 95% confidence interval 1.05-1.52) when compared with a referent group of men reporting 7 to 8 hours/day of sleep. Similar associations were not revealed in women.

CONCLUSIONS: Short sleep duration was significantly associated with elevated serum CRP concentration independent of waist circumference and moderate physical activity in men but not in women.

 

[Vince]

The Daily Telegraph reports:

"The most at-risk group was adults under 60 years of age who slept five hours or fewer a night. They increased their risk of developing cardiovascular disease more than threefold ... Women who skimped on sleep ... were more than two-and-a-half times as likely to develop cardiovascular disease."
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