Shoud I start Adex?

[jsmith21896]

I'm on .4 (80mg) of test cyp e3.5d, was taking .5 of adex 2 times per week, felt bad last month so I check E2 with sensitive test, came back as 18 (8-35 from labcorp). Rechecked almost 6 weeks after last Adex dose, I am now at 39.5. My question is, am I high enough to take a smaller dose (.25 2 times per week)? I do seem to have some symptoms, low libido, some anxiety. Thanks.

 

[Nashtide]

I'm on .4 (80mg) of test cyp e3.5d, was taking .5 of adex 2 times per week, felt bad last month so I check E2 with sensitive test, came back as 18 (8-35 from labcorp). Rechecked almost 6 weeks after last Adex dose, I am now at 39.5. My question is, am I high enough to take a smaller dose (.25 2 times per week)? I do seem to have some symptoms, low libido, some anxiety. Thanks.

Post the rest of your labs with ranges.

 

[jsmith21896]

CBC With Differential/Platelet
WBC 7.0 x10E3/uL 3.4 - 10.8 01
RBC 5.90 High x10E6/uL 4.14 - 5.80 01
Hemoglobin 17.6 g/dL 12.6 - 17.7 01
**Effective December 4, 2017 the reference interval**
for Hemoglobin MALES only will be changing to:
Males 13-15 years: 12.6 - 17.7
Males >15 years: 13.0 - 17.7
Hematocrit 52.4 High % 37.5 - 51.0 01
MCV 89 fL 79 - 97 01
MCH 29.8 pg 26.6 - 33.0 01
MCHC 33.6 g/dL 31.5 - 35.7 01
RDW 12.4 % 12.3 - 15.4 01
Platelets 167 x10E3/uL 150 - 379 01
Neutrophils 61 % Not Estab. 01
Lymphs 28 % Not Estab. 01
Monocytes 8 % Not Estab. 01
Eos 3 % Not Estab. 01
Basos 0 % Not Estab. 01
Neutrophils (Absolute) 4.2 x10E3/uL 1.4 - 7.0 01
Lymphs (Absolute) 1.9 x10E3/uL 0.7 - 3.1 01
Monocytes(Absolute) 0.6 x10E3/uL 0.1 - 0.9 01
Eos (Absolute) 0.2 x10E3/uL 0.0 - 0.4 01
Baso (Absolute) 0.0 x10E3/uL 0.0 - 0.2 01
Comp. Metabolic Panel (14)
Glucose, Serum 88 mg/dL 65 - 99 01
BUN 28 High mg/dL 6 - 24 01
Creatinine, Serum 1.44 High mg/dL 0.76 - 1.27 01
eGFR If NonAfricn Am 60 mL/min/1.73 >59
eGFR If Africn Am 70 mL/min/1.73 >59

TESTS RESULT FLAG UNITS REFERENCE INTERVAL LAB
BUN/Creatinine Ratio 19 9 - 20
Sodium, Serum 139 mmol/L 134 - 144 01
Potassium, Serum 4.3 mmol/L 3.5 - 5.2 01
Chloride, Serum 99 mmol/L 96 - 106 01
Carbon Dioxide, Total 27 mmol/L 18 - 29 01
Calcium, Serum 9.2 mg/dL 8.7 - 10.2 01
Protein, Total, Serum 7.0 g/dL 6.0 - 8.5 01
Albumin, Serum 4.6 g/dL 3.5 - 5.5 01
Globulin, Total 2.4 g/dL 1.5 - 4.5
A/G Ratio 1.9 1.2 - 2.2
Bilirubin, Total 0.4 mg/dL 0.0 - 1.2 01
Alkaline Phosphatase, S 63 IU/L 39 - 117 01
AST (SGOT) 25 IU/L 0 - 40 01
ALT (SGPT) 25 IU/L 0 - 44 01
Testosterone, Serum 1101 High ng/dL 264 - 916 01
Adult male reference interval is based on a population of
healthy nonobese males (BMI <30) between 19 and 39 years old.
Travison, et.al. JCEM 2017,102;1161-1173. PMID: 28324103.

 

[Vince Carter]

Wheres you E2 testing...don't post a number I want to see the lab range for the test that was given to you to know if you had the Ultra Sensitive LC/MS/MS test that is for males.

Added that .5mg 2XW is a horribly high dose, your most recent number of 39.5 if that was the correct test is not high and in and of itself does not warrant an AI.

 

[jsmith21896]

It was a separate test, I gave it in the first post, it was the LC/MS/MS both times

 

[Vince Carter]

I was looking in post #3 where an E2 would make more sense in relation to the others taken at the same time, snapshotting just one thing absent the rest isn't too helpful. But I'll stay with saying no AI, 39 isn't high inspite of what LabCorp says.

 

[jsmith21896]

somebody wanted the rest of my labs, that was my most recent from 11/20/17, he didn't order the E2 and when he does, he doesn't order the LC/MS/MS so I do it on discountedlabs. The E2 that showed 18 was a few days before the rest was done, I stopped and retested again, only the E2 about 5.5 weeks later.

 

[Nashtide]

somebody wanted the rest of my labs, that was my most recent from 11/20/17, he didn't order the E2 and when he does, he doesn't order the LC/MS/MS so I do it on discountedlabs. The E2 that showed 18 was a few days before the rest was done, I stopped and retested again, only the E2 about 5.5 weeks later.

Okay so your TT is too high which is causing your Hct, rbc and hemoglobin to be high. You really need to drop your T dose or your in danger. If you reduce your dose by 20% you will still have T levels at the very top of the normal range and the reduction in T cyp will drop your E2 to around 30. So a win-win. You won't stroke out and you won't need an AI.

 

[jsmith21896]

Okay so your TT is too high which is causing your Hct, rbc and hemoglobin to be high. You really need to drop your T dose or your in danger. If you reduce your dose by 20% you will still have T levels at the very top of the normal range and the reduction in T cyp will drop your E2 to around 30. So a win-win. You won't stroke out and you won't need an AI.

I did donate today to help with the elevated hct levels. I will lower my dose a bit, thanks.

 

[FeelingLost]

Okay so your TT is too high which is causing your Hct, rbc and hemoglobin to be high. You really need to drop your T dose or your in danger. If you reduce your dose by 20% you will still have T levels at the very top of the normal range and the reduction in T cyp will drop your E2 to around 30. So a win-win. You won't stroke out and you won't need an AI.

jsmith did not say when he took his blood sample that TT might not be his trough. Heck many doc want to see the peak or just don't care when you draw bloods. I find it hard to believe anyone is going to stroke out on 80mg/week. Hell most of the guys here are taking >120/wk

If this were me I would take .25mg/week AI and keep everything else the same until next blood test where I would make sure I was in my trough.

jsmith do you inject Monday morning and Thursday night? If so I draw blood Monday morning 8-9am before your shot. This will show your lowest T lvl what the guys around here call the trough. You will also get the best E2 reading as well.

When my E2 is high I get weepy at TV, gain water weight and my nipples hurt. No anxiety or libido issues.

 

[jsmith21896]

jsmith did not say when he took his blood sample that TT might not be his trough. Heck many doc want to see the peak or just don't care when you draw bloods. I find it hard to believe anyone is going to stroke out on 80mg/week. Hell most of the guys here are taking >120/wk

If this were me I would take .25mg/week AI and keep everything else the same until next blood test where I would make sure I was in my trough.

jsmith do you inject Monday morning and Thursday night? If so I draw blood Monday morning 8-9am before your shot. This will show your lowest T lvl what the guys around here call the trough. You will also get the best E2 reading as well.

When my E2 is high I get weepy at TV, gain water weight and my nipples hurt. No anxiety or libido issues.

I inject 80mg every 3.5 days, 160mg per week. I inject Sunday evening and Thursday morning, the lab with the Testosterone was taken on Tuesday around 4:00pm, basically half way between injections, probably closer to my peak. The latest E2 was taken on Saturday morning.

 

[FeelingLost]

I inject 80mg every 3.5 days, 160mg per week. I inject Sunday evening and Thursday morning, the lab with the Testosterone was taken on Tuesday around 4:00pm, basically half way between injections, probably closer to my peak. The latest E2 was taken on Saturday morning.

Sorry my bad I miss read your first post. 160/week!?! Cold turkey? You did not try 100/wk or 120/wk first?
Ok well 160's a lot. I take back all my recommendations. If you plan to stick with 160 I'd take your AI @ .5mg/wk You already know how powerful adex is.

If I can ask what was your SHGB? Is it really high?

Just to give you a little prespective I've been on TRT form 12 months and only last month did my doc give me 150mg/week .25 MWF and I am very worried it might be too much. My Ai is .125 EOD and I take 900iu's HCG. I'm 3 weeks in and can't say I feel any different than before the 150.

Here's alittle clip and paste from Gman86 it will help bring home what your 160 will end up being.

-Gman86
Also remember, when you reach a steady state of a medication, you will have double the amount of milligrams in your system of the dose you are taking in-between each half life. This is kind of complicated, but it doesn't matter how you space out the dosages or how often you take it. For example, 1mg taken EOD, or 0.5mg taken everyday. It's still 1mg taken within one half life or Arimidex which is 2 days. So another example is test cypionate. Doesn't matter if you take 100mg once per week or split that into 50mg twice per week or 14mg everyday. As long as it's 100mg within one half life, which is 8 days for test cyp. So by 5 half lives of the medication, which would be 40 days for test cyp, you will have double the amount of medication in your system. Which would be 200mg. This part is pretty complicated, but just remember, whatever the dosage you are taking of a medication, after 5 half lives you will have double the amount of medication in your system compared to starting.

hth

 

[Maximus220rr]

Jsmith21896 are u using hcg? Dose? And anastrozle?