Yeppers... I have SOMETHING going on also.
Long story short:
1. PSA creeping up past 4.
2. URO wanted to do a biopsy.
3. No way ...
4. URO did 4K test and good results.
5. PSA kept on going up to 8.
6. URO wanted to do a biopsy.
7. No way....
8. Did a 3T-MP-MRI of the prostate.
9. Nothing jumped out and it was PIRAD 2. PIRAD 1 is nothing at all. Nothing detectable at that time.
10. In between all of this I was on different antibiotics.
11. Tracked down my old URO and went to see hm.
12. I was on week 7 of 2 months on CIPRO.
13. I ordered a bunch of PSA test on my own and when I was on some antibiotics PSA went down.
14. My old URO was hedging toward the biopsy.
15. Last thing he did was the obligatory DRI... OUCH!!!!
16. It was like a T.V. travel monologue ... O.K. lower right feels O.K. .... O.K. lower top feels O.K. ...... All the way to the top. Did say I was textbook case of BPH

17. After the DRI I had some discharge on the tip. "Don't whip it off....." Searching for a glass slide, and away he went to a microscope somewhere, like a little kid with a new toy....
18. "Hmmmm... something going on in your prostate." I think he said pus or something like that. Was not talking biopsy at least

19. "Lets change antibiotics to BACTRM 500mg twice a day for 2 months."
20. I had ran a PSA 2 weeks prior ( after about 6 weeks on CIPRO) and was heading south slowly. (6.1)
21. Did a PSA test about a week after starting the BACTRIM and it was 7.9.
22. I will do another PSA test before I see him in a few weeks.
23. To Be Continued
As per the antibiotics, my TRT DOC is a retired A.F. DOC. Like the insurance company... Seen a lot.... Knows a lot....
He indicates that prostate infections can be hard to get under control. Something about the makeup of the gland and it takes a loooooooooooong time for any antibiotics in the blood to reach all the nooks and crannies. If you don't get ALL the bacteria killed off you end up with a recurring infection.... Says some folks end up on a maintenance dose of Doxy to keep from getting reinfected. BTW he also says 30 to 60 days on initial treatment.... So I would keep taking all your antibiotics till all gone.