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The Impact of Step Reduction on Muscle Health in Aging: Protein and Exercise as Countermeasures
REVIEW ARTICLE Front. Nutr., 24 May 2019 | The Impact of Step Reduction on Muscle Health in Aging: Protein and Exercise as Countermeasures The Impact of Step Reduction on Muscle Health in Aging: Protein and Exercise as Countermeasures Sara Y. Oikawa, Tanya M. Holloway, and Stuart M. Phillips*...
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A Five-Ingredient Nutritional Supplement and (HBRE) Improve Lean Mass and Strength in Free-Living Elderly
Abstract: Old age is associated with lower physical activity levels, suboptimal protein intake, and desensitization to anabolic stimuli, predisposing for age-related muscle loss (sarcopenia). Although resistance exercise (RE) and protein supplementation partially protect against sarcopenia under...
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The Effects of Cow-Milk Protein Supplementation in Elderly Population:
The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis Abstract Background To review the currently available evidence on the effect of cow-milk protein supplementation (CPS) on health in the elderly. Methods Five electronic...
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Three Questions with Sarcopenia
Three Questions with Sarcopenia 2 Principal Investigators Dr. Shalender Bhasin and Dr. Peggy Cawthon https://fnih.org/news/announcements/three-questions-with-sarcopenia2-principal-investigators September 21, 2020 — The FNIH Biomarkers Consortium Sarcopenia 2 project, Sarcopenia as a Valid...
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Effect of T supplementation on sarcopenic components in middle-aged and elderly men
ABSTRACT The aim of this study was to conduct a systematic review of the literature of randomized controlled trials on the effect of testosterone (T) supplementation compared to the placebo group or lower dose on sarcopenic components (muscle mass, strength, and physical performance) in...
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How to Increase Muscle Mass in Critically Ill Patients
Abstract Purpose of Review Decades of research on nutrition and exercise for athletes and bodybuilders have yielded various strategies to promote anabolism and improve muscle health and growth. We reviewed these interventions in the context of muscle loss in critically ill patients...
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Creatine in Health and Disease
Abstract Although creatine has been mostly studied as an ergogenic aid for exercise, training, and sport, several health and potential therapeutic benefits have been reported. This is because creatine plays a critical role in cellular metabolism, particularly during metabolically stressed...
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Can conditions of skeletal muscle loss be improved by combining exercise with anabolic agents?
Abstract Sarcopenia, cachexia, and atrophy due to inactivity and disease states are characterized by a loss of skeletal muscle mass, often accompanied by reduced levels of anabolic hormones (e.g. testosterone). These conditions are associated with an increase in mortality, hospitalization, and...
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Insights of sports nutrition science to support active aging in healthy older adults
Abstract Skeletal muscle mass losses with age are associated with negative health consequences, including an increased risk of developing metabolic disease and the loss of independence. Athletes adopt numerous nutritional strategies to maximize the benefits of exercise training and enhance...
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Understanding the effects of nutrition and post-exercise nutrition on skeletal muscle protein turnover
Summary Skeletal muscle is the largest organ of the human body and plays a pivotal role in whole-body homeostasis through the maintenance of physical and metabolic health. Establishing strategies aimed at increasing the amount, and minimizing loss, of muscle mass are of utmost importance...
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Role of androgens and SARMs in cachexia
Cachexia is a complex wasting syndrome, accompanying a variety of end-stage chronic diseases, such as cancer, heart failure, and human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS). It significantly affects patients’ quality of life and survival. Multiple...
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Effects of creatine supplementation on sarcopenia, osteoporosis, frailty, and Cachexia?
Creatine supplementation for older adults: Focus on sarcopenia, osteoporosis, frailty, and Cachexia (2022) Darren G. Candow, Philip D. Chilibeck, Scott C. Forbes, Ciaran M. Fairman, Bruno Gualano, Hamilton Roschel ABSTRACT Sarcopenia refers to the age-related reduction in strength, muscle...
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The anabolic applications of androgens in older adults with functional limitations
The anabolic applications of androgens in older adults with functional limitations (2022) Arijeet K. Gattu · Anna L. Goldman · Ezgi Caliskan Guzelce · Francesca Galbiati · Shalender Bhasin Abstract Aging is associated with a progressive decrease in skeletal muscle mass, strength, and power...
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Male sex hormones, aging, and inflammation
Male sex hormones, aging, and inflammation (2023) Justin M. Ketchem · Elizabeth J. Bowman · Carlos M. Isales Abstract Adequate levels of androgens (eugonadism), and specifically testosterone, are vital compounds for male quality of life, longevity, and positive health outcomes. Testosterone...
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