Low DHEA value

[Phoenix]

Just got my labs back.

DHEA, serum = 40ng/dl Reference Interval for above 19 years of age is 31 - 701

My question is would I benefit from taking DHEA supplements to increase this value?
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Other values:

Total T = 1090 ng/dL
Free T = 22 pg/dL
Estradiol = 54.9 pg/mL (Increasing my anastrozole)
SHBG = 45 nmol/L
IGF-1 = 105 ng/mL

 

[Gene Devine]

Yes, it is beneficial to "back-fill" your pathways when on TRT.

One should supplement both DHEA and Pregnenolone at 50 mg each of a micronized slow release formula.

Go here: www.dhea.com for both.

 

[Vince Carter]

Im wary of DHEA, had some bad experience with it before i was on any TRT. I was taking 100mg at one point and felt terrible, what I now suspect was easy conversion to E2, with untreated Low T. Too, my last bloods DHEA-S was low @ 160 (70-495 mg/dl)..so I'm wary of adding another variable at this point especially from that past experience. I know I could try 25mg but...I'm not sure.

 

[Gene Devine]

Im wary of DHEA, had some bad experience with it before i was on any TRT. I was taking 100mg at one point and felt terrible, what I now suspect was easy conversion to E2, with untreated Low T. Too, my last bloods DHEA-S was low @ 160 (70-495 mg/dl)..so I'm wary of adding another variable at this point especially from that past experience. I know I could try 25mg but...I'm not sure.

100 mg is too much.

You can do 25 mg twice daily to better tolerate.

Do you have labs that show DHEA converted to higher E2 levels?

You have low DHEA-S levels and it would be beneficial for you health to get these to higher levels.

 

[Vince Carter]

No E2 testing as I said that was Pre anything TRT and was entirely anecdotal of starting and stopping that dosage and feeling "better" 3 days after stopping it. I'd take it and almost immediately feel like a hormonal female. I'm open to 25mg.

 

[Vettester Chris]

OP, as noted, your DHEA serum is down at the bottom end. I agree completely that your are a prime candidate for some form of replacement therapy, HOWEVER, I strongly suggest that you also run a 24 hour cortisol saliva test & a complete thyroid panel, and have it reviewed.

In "certain" instances, the adrenals can be in a maladaptated phase when DHEA slumps, where cortisol production will also be effected. So reviewing a cortisol-DHEA correlation profile "IMO" is essential before jumping too far in. Adrenal productivity will also factor in with your thyroid, which again is why all 3 should be considered. It could also just be simple deficiency, maybe prompted upstream from lower pregnenolone levels, which is common, and is why supplementing both hormones can be beneficial.

 

[Vince Carter]

I have 25mg DHEA as a small step I want to do one a day dosing does AM or PM make a difference?

 

[Vettester Chris]

I have 25mg DHEA as a small step I want to do one a day dosing does AM or PM make a difference?

Yeah, definitely do it in the morning ...

 

[Phoenix]

Thanks all !

 

[Vince Carter]

I swear that everytime I use DHEA, 1 tab/25mg for four days, I feel angry, aggressive and short-tempered. Not sure what's going on but I'm not taking it after today.

 

[Gene Devine]

I swear that everytime I use DHEA, 1 tab/25mg for four days, I feel angry, aggressive and short-tempered. Not sure what's going on but I'm not taking it after today.

Never heard of that happening but who knows, we're all different I guess.