Losartan and creatinine levels

[HealthMan]

Anyone using losartan noticed an increase in serum creatinine levels? I was reading about it and it seems like one possible side effect but the population studied was old and with many health issues

 

[Vince]

Read this very interesting thread. You will learn a few things.

Can Losartan decrease high hematocrit caused by testosterone replacement?

https://www.excelmale.com/forum/threads/blood-pressure-meds.15169/#post-119001

 

[Vince Carter]

Read this very interesting thread. You will learn a few things.

Can Losartan decrease high hematocrit caused by testosterone replacement?

https://www.excelmale.com/forum/threads/blood-pressure-meds.15169/#post-119001

Did you link the wrong thread because there's not a word there about Creatinine.

 

[Vince Carter]

Anyone using losartan noticed an increase in serum creatinine levels? I was reading about it and it seems like one possible side effect but the population studied was old and with many health issues

Ive not seen that on the forum that I can think of. You're a gym guy, right? High protein diet? Use Creatine???

 

[HealthMan]

Ive not seen that on the forum that I can think of. You're a gym guy, right? High protein diet? Use Creatine???

I am a gym guy. And i read about ARBs potentially increasing creatinine. I will start losartan to help lower my BP at work (at home it is below 125/75) but at work it spikes. Just wondering if anyone here experienced an increase in creatinine after starting lasartan.

 

[Vince Carter]

I jsut ask because we know gym etc can elevate creatinine. Good luck with your BP.

 

[Nelson Vergel]

Losartan can actually decrease creatinine. Are you taking any supplements that may be causing this increase?

 

[Nelson Vergel]

"...there has been a wide variety of studies conducted with losartan. It has shown benefit in controlling hypertension, decreasing proteinuria, slowing the progression of type 2 diabetic nephropathy, and decreasing the risk of stroke in certain populations. In addition, favorable surrogate markers such as decreased platelet aggregation decreased uric acid, decreased proteinuria, and regression of LVH (left ventricular hypertrophy) have also been documented. For a first in class medication, which is touted as being a weaker angiotensin receptor blocker, it has shown remarkable outcomes. "

"...the overall effect of losartan on GFR can be variable, depending on whether the blood pressure remains in the renal autoregulatory range. If the blood pressure is within this range, losartan is associated with an increase in GFR (decreased creatinine). However, with low blood pressure, it may be associated with decreased, increased, or unchanged GFR."

Reference:
Fifteen years of losartan: what have we learned about losartan that can benefit chronic kidney disease patients?

 

[Nelson Vergel]

Click here:

More losartan information posted on ExcelMale.com

 

[HealthMan]

Losartan can actually decrease creatinine. Are you taking any supplements that may be causing this increase?

Hi Nelson
I just started losartan so not experiencing any increase. However i have read many studies showing that losartan increases creatinine. However the population is these studies were older and with many health issues. one of these studies below:

https://www.bmj.com/content/356/bmj.j791.full.print

 

[Timeattackguy]

There is a positive correlation between losartan and creatinine levels. Unfortunately, the literature does not document studies done on young individuals targeting muscle growth and fat loss.

 

[HealthMan]

A little over 1 week using losartan and my HR is on average 10 higher (rest HR was 67-70 before bow is 76-80). I have read that this can happen with the body trying to compensate for the lower blood pressure and it might be temporary. Lets see. If it is not temporary i will probably drop the losartan because. Higher HR causing me anxiety

 

[HealthMan]

A few weeks using losartan 50mg a day. Heart rate back to normal. And blood pressure around 110/70. Tired feeling almost entirely gone