madman
Super Moderator
Join Dr. Geo as he delves into the genetics behind prostate cancer with Dr. Eric Klein, a renowned expert in the field. This episode covers the role of genetic predispositions, the science behind liquid biopsies, and their application in cancer detection, particularly prostate cancer. Dr. Klein, the emeritus professor at Cleveland Clinic and current researcher at Gallery, discusses how next-generation sequencing is revolutionizing early cancer detection and the promising future of these advancements.
Learn how genetic mutations, epigenetics, and methylation play a crucial role in cancer development and treatment decision-making. Whether you are a health advocate or practitioner, this episode provides actionable insights into prostate cancer management. Additionally, discover the innovative Galleri test and its accuracy in detecting multiple cancers through a simple blood test.
Chapters
00:00 Liquid Biopsy for Early Detection of Prostate Cancer | Eric Klein, MD
02:59 Genetics and Prostate Cancer
06:12 Epigenetics and Gene Regulation
07:55 Somatic vs. Germline Mutations
10:50 Liquid Biopsy
17:42 Future of Cancer Monitoring
20:14 Liquid Biopsy in Clinical Practice
27:42 Pathfinder Study: Screening 6,600 Asymptomatic Individuals with the Galleri Blood Test
31:19 Understanding the Targeted Methylation Assay
33:19 Prostate Cancer Detection and Prognosis
34:28 Galleri Test and Prostate Cancer Screening
38:04 Biologic vs. Histologic Cancer Assessment
42:18 Implications of Non-Shedding Tumors
49:15 Future of Cancer Screening and Treatment
52:51 Coverage and Accessibility of Galleri Test
