I recently had an mri because of an elevated prolactin level on blood work. There is a small mass on my pituitary gland. Im bringing this up on this forum because over the last few years there has been a backlash against ai's. There actually is some research showing elevated estrogen causing hyperprolactinemia. I also saw some case reports of men with prolactinomas who started trt but had to stop because prolactin levels increased alot. When I started trt I used arimidex but I stopped because it negatively effected my sex drive. The last few years I havent used any ai's. This past year I did two test only cycles. First cycle was 350 test for eight weeks. The second cycle was 500 test for eight weeks. The first cycle I used nolvadex 20 mg three times per week. The second cycle I used arimidex .25mg twice per week. Im wondering if my lack of estrgen control during these cycles played any role in my prolactinoma development? I know ill never find the answer to that question. Looking forward should I be using an ai with my trt? I know my GP will want me to stop trt. My trt is prescribed through defy. Im worried that if i stop my body wont have any chance to recover because the elevated prolactin will stop my natural testosterone production.