Clomid safe with low estradiol ?

[aluminex]

I’ve stopped TRT due to some medical issues. However, I crashed my estrogen with too much AI. I’d like to start Clomid for PCT, but wondering if Clomid will lower my estrogen making my e2 recovery slower.

 

[Vince]

Clomid will raise your estrogen not lower it, stimulation of the testes where aromatase happens pretty easily.

 

[aluminex]

Clomid will raise your estrogen not lower it, stimulation of the testes where aromatase happens pretty easily.

Thank you

 

[lowe2sucks]

Clomid will raise your estrogen not lower it, stimulation of the testes where aromatase happens pretty easily.

but doesn't it block the estrogen action on the brain?

 

[Vince]

but doesn't it block the estrogen action on the brain?

My understanding is clomid blocks E2 at the hypothalamus/pituitary level. The brain goes I have no E2, that means I have no T", and so it secretes LH/FSH to stimulate the testicles to produce more T. As long as a man isn't primary and he creating ample LH/FSH from the clomid stimulation, his T (and resulting E2) will rise. The brain still doesn't "see" the E2 because the clomid continues to block it, so the body keeps stimulating with LH/FSH.

 

[aluminex]

I started taking 12.5 dose per day. However, yesterday my right side began to hurt, so I am assuming it's my liver as my liver enzymes have been crazy since beginning a less than perfect protocol.

Any ideas on what I could do to remedy? I am going to make a doctors appointment to follow-up, but I'm wondering if anyone has experienced similar with Clomid, or TRT in general.