tadalifil: 15 years journey

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  1. madman

    Tadalafil: 15 years' journey in male erectile dysfunction and beyond

    Abstract Tadalafil, Cialis, Eli Lilly & Co./ICOS, (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12ahexahydropyrazino[10,20:1,6] pyrido[3,4-b]indole-1,4-dione, was first discovered in 2003. It was reported to have high diastereospecificity for phosphodiesterase 5 (PDE5) inhibitions...
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