post finasteride syndrome

This review critically examines Post-Finasteride Syndrome (PFS), a condition eventually reported by men who have used finasteride for androgenetic alopecia or benign prostatic enlargement and experienced persistent adverse effects after discontinuation. We explore the clinical manifestations...

https://www.sciencedirect.com/science/article/pii/S0091302223000626

It’s been almost a year since I started taking 400mg of pregnenolone a day in the morning on an empty stomach. I’ve tried different brands but settled on the Double Wood brand from Amazon for the price and effectiveness. Had a brief time where I tried stopping here and there and didn’t feel as...

Finasteride is what originally lead me to all of this. Reading into things more lately, I read some people saying that the presence of 5AR metabolites like DHT up regulate 5AR in a positive feedback loop. Does anyone have any knowledge or experience with this?

ABSTRACT Background: An organic etiology underpinning post-finasteride syndrome, a constellation of persistent sexual, neuropsychiatric, and somatic symptoms reported by men exposed to 5-alpha-reductase inhibitors (5ARIs), is debated. Persistent changes in neurosteroid levels or androgen...