Understanding the Influence of Genetic Differences on SHBG Hormone Levels in Men
The Connection Between Genetics and Hormone Binding
Our bodies are finely tuned systems where even the smallest changes can have significant impacts. This is especially true with hormones, the chemical messengers...
Hi guys, I have couple of questions about my TRT protocol.
1) In my last labs, SHBG came back low (1 unit below normal range). What effect does that have on things like libido, EQ, etc.? Is it necessary to raise it?
2) Unrelated to #1... from time to time my estradiol has been high. Doctor...
Hi guys, I have been a very long lurker on this and other related forums. I am 31 years old male , been battling with low T all my life (more aware of it since 20 years old). Unfortunately I have never been able to experience any difference in my symptoms with all types of therapies , so i am...
There are some topics here and in other forums (please Google "TRT and ED" on Reddit or other forums) of men complaining about having ED on TRT after being good and dialed for months or even years and suddently developing impotence out of nowhere.
Suspects are: estrogen imbalances, low SHBG...
So this relates to all forums, Reddit, various YouTube videos from doctors, pretty much every internet information source.
As of the past few years all the rage and focus is on FT. So much so that certain tests are referred to with derogatory names. “Piss poor”. That’s how important FT is to...
Started the Keto Diet October LY. A1c 6.0, fasted Glucose 128, BP 140/85. 20 lbs over weight. Doc was alarmed with my steady increase in certain blood markers and possible insulin resistance and encouraged me to act.
Fast forward I guess the results are what you would typically expect to...
Hypothetically the elevation of T in the blood could be smoother with sustanon, so I would like to know if anyone has tested frequent microdoses with it.
The idea of using small doses of test with small doses of deca would be to maintain good levels of e2, which are crushed by deca and have...
I want to thank everybody on the forum who wrote about low shbg and TRT.
I read several posts and now I would like to suggest a sequence with data from each user who is willing to share it, so that it is compiled and we can use it as a base.
So I would like to hear from everyone who has low...
My TRT SHBG is 16 which is kinda low. I've read TRT lowers SHBG, but by how much? Is is possible my natural SHBG is around 16? I don't have bloodwork that measured SHBG pre TRT
Hi everyone,
Just a theory I've been having.
I started doing daily dosing recently and it's probably the best I've felt since staring TRT. I'm a low SHBG by the way (around 20).
But my main issue is insomnia and I'm curious if this is caused by having a steady state of high test levels.
So...
I'm on Test Prop @ 15mg ED SQ and Armour Thryoid 3 grains.
For the past 2 1/2 months, I have noticed my hair is rapidly thinning and dry, my beard/stache seems to be growing slower looking mildly sparcer and not as dark.... Energy, mood, libido and sleep sucks... I suspected high E possibly...
Hi everyone - relatively new to TRT. About 3 months. This is my first labs since starting. Paid for on my own so not comprehensive, but has Estradiol, Testosterone, Free T, and SHBG.
I feel ok, not great. Definitely better than pre TRT I would say, but not optimal. I’d say major issues are some...
Long story short I decided to switch from weekly IM injection's to micro dosing. If you're interested why info is here.
https://www.excelmale.com/forum/threads/struggling-with-getting-dialed-in.23549/
My doctor is challenging my new protocol and he wants me to send him references / studies...
My SHBG has run in the 12-15 range with pretty much any TRT changes I have made. My protocol last month was T Cyp (SQ) 24mg x3/wk, HCG 200 iu 3x wk, DHEA 25 mg 3 x wk, Pregnenolone 50mg 3 x wk, and T Cream to scrotum each night, a very small dose. Seemed to work, and a set of labs found DHT was...
i always see people recommending low shbg people for ED injections, but don't know why. anyone can explain the logic and details behind this?
the test leaves their body too fast?
Been on 10mg cypionate IM a day for 5 weeks.
prolactin and E2 are on the high end. I got a prescription for 0.0625 AI pills, I am considering starting with 3x a week.
1. Is my prolactin High due to my e2 and should it follow e2 down if i take ai? should i add in p5p?
2. I have my honeymoon in...
]My Family Doc is ready to offer me TRT but I was hesitant given my age (32). He said we could try a round of HCG Mono to "jump start" my system. I just finished my second week of HCG - 1,000 its every 72 hours.
I've been experiencing low T symptoms since my early 20s - biggest symptom being...
Hi,
Has anyone used Aromatase Inhibitor for long time? I would like to know whats your thought on this? What are the side effects. It would be helpful if there is no serious side effects for low shbg guys.
FYI: I am on low TRT dosage and I am trying to avoid AI but just wondering if anybody...
I am low shbg, daily injector, trying to get my E2 from 39 to the low 20's. Libido is my biggest issue. Feel free to see my other thread regarding my protocol.
https://www.excelmale.com/forum/threads/low-libido-low-shbg-protocol-help-labs-x3.21084/
I have used 0.25 ai once or twice a week on...
Has anyone dealt with something similar? Libido seems to be illusive and hard to find. I am a low SHBG and struggle with libido/erections. daily injector IM (9mg x 7 = 63 mg week)
The only time I have felt normal in that sense (libido) is usually when I am coming off TRT (for a week or two). Or...
I started TRT 4 weeks ago. I spent a few months doing a solid research to educate myself before starting. I went so several doctors and quickly realised that there is not a single doctor in my country who is even remotely familiar with TRT. So my only option was to self-medicate.
My symptoms...
This is what happened
Injection alone - Doesn't do shit for me no matter what protocol
Cream 2x a day - Felt Amazing, but due to horrible hair loss I stopped it but it was a miracle
Cream 1x a day - Felt great, not as great as 2x. Say about 75% of what I felt on 2x
now I'm doing injection +...
Hello, this is my first post in the forum. I hope i can get some help.
I was diagnosed with hypogonadism because I had the symptoms (erectile disfunction, low libido, low energy, fatigue, brain fog, anxiety) and also my Free T was 10pg/ml which is very low, especially for my age. Total T around...
For the guys who have labs on both . Does your SHBG tend to differ with injectable and Scrotal cream ?
My SHBG goes from mid 20s to low teens on ANY dose or frequency of Test cyp .
I was wondering if Cream is different ?
Please let me know I am desperate.
So I'm a long time lurker on the forum first off I wanna say that thanks to this forum. I have been able to recover from the damage. I have done to my body with steroid abuse during my competition days.
My situation is a typical low SHBG case but I have managed to find a protocol that works 90%...
I'd love to hear from any of you that have low SHBG (say < 18 nmol/L) and had bad results injecting testosterone, then switched to scrotal cream (either alone or in conjunction with injections). What was your experience? I am primarily asking about libido/ED/sexual function, but any other areas...
17-21 SHBG here, so fucking random mood, energy, libido usually gone, sometimes there, erections sometimes hard, many times weak.
Done weekly and 2 times a week injections, all kinds of arimidex protocol and it just doesnt fucking work.
Thinking of trying ED or EOD injections, anyone had...
So for about the past month I had weaned off of arimidex in hopes of feeling better. I was using the 1mg adex/100mg test strategy prior to weaning off. E2 was around 21 and tt was at 1000ish. Felt awful, no sex drive, fatigue, aches and pains, hair shedding, mentally slow, brain fog, dark...
So for the first 4 months or so of trt at 200mg test cyp per week with minimal ai usage. .25 anastrozole maybe once every 5 days or so, I felt good. Great workouts, insane pumps, crazy libido. Then I started reading on here about trying to stay within the low 20s on e2. So I began using the...
J Urol. 2017 May;197(5):1326-1331. doi: 10.1016/j.juro.2017.01.018. Epub 2017 Jan 10.
The Utility of Sex Hormone-Binding Globulin in Hypogonadism and Infertile Males.
Ring J1, Welliver C2, Parenteau M3, Markwell S1, Brannigan RE4, Köhler TS5.
Abstract
PURPOSE:
We sought to determine the role...
Anyone with experience? With SHBG around maybe 18-20, and if u inject doses over 50mg, could that mess things up which gives you low libido and/or ED?
If so, is this due to high free T and free E spikes or what is exactly going on?
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