There have been quite a few research studies on lack of sleep, like how it can increase the risk of heart attack and stroke, contribute to brain aging, and even make you feel drunk at work (not as fun as it sounds.) If you don’t get enough REM sleep, your brain has trouble maintaining all sorts...
I know High E2 can cause depression, low motivation, low energy, etc.... especially if one is low SHBG then you are even more sensitive to E2 issues...
I was wondering could High E2 cause someone to also be less affected by stimulants, etc.... Possibly could E2 affect dopamine levels as well?
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