inflammation/endothelial dysfunction

They are finally realizing that anything promoting blood vessel inflammation, in this case excess niacin metabolites, can lead to cardiovascular disease. It's not the cholesterol. https://consultqd.clevelandclinic.org/link-discovered-between-excess-niacin-and-cardiovascular-disease

Abstract Maintenance of endothelial cell integrity is an important component of human health and disease since the endothelium can perform various functions including regulation of vascular tone, control of hemostasis and thrombosis, cellular adhesion, smooth muscle cell proliferation, and...