They are finally realizing that anything promoting blood vessel inflammation, in this case excess niacin metabolites, can lead to cardiovascular disease. It's not the cholesterol.
https://consultqd.clevelandclinic.org/link-discovered-between-excess-niacin-and-cardiovascular-disease
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433562/
Galectin-3: a novel biomarker for the prognosis of heart failure
HILMAN ZULKIFLI AMIN, LUKMAN ZULKIFLI AMIN, and IKA PRASETYA WIJAYA
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Abstract
Heart failure...
Do you know if there's any contradiction with TRT and HCG (300 iu's twice a week) with someone who has very mild coronary artery disease? I'm trying to regain fertility over the next year and I'm going the slow and steady route.
Yeah I know it is in a meathead magazine but it was put together by some educated meatheads and really gets at what we've been trying to figure out relative to nandrolone and HRT. It also contains that 4 letter word we don't use on this site either. The use of ARBs or ACEi is one worth noting...
It's an animal study, but probably relevant to men. It's best not to eat an unhealthy diet, but it's good to know that testosterone protects against heart artery damage. The abstract says:
"To gain insights into the role of testosterone in the development of atherosclerosis and its related...
https://drmalcolmkendrick.org/2016/01/18/what-causes-heart-disease/
Of course, by heart disease I mean the thickenings and narrowings in the larger arteries in the body (atherosclerotic plaques). I am also focussing almost entirely on the arteries supplying blood to the heart (coronary...
Cochrane Review has published a new meta-analysis on the relation between saturated fat in the diet and cardiovascular disease. Their results showed that reducing saturated fat reduced cardiovascular disease (CVD) events, but not morality. The abstract said:
"We included 15 randomised...
From the abstract:
Whether androgen deficiency among men increases the risk of cardiovascular (CV) events or is merely a disease marker remains a subject of intense scientific interest.
In this post hoc analysis of men with available baseline plasma T concentrations, we examined the...
If you've watched the documentary "The Widowmaker," you know the calcium artery score is a marker for risk of heart attack. A recent study, reported at an AIDS conference but not yet published, found more coronary artery calcium progression among HIV+ men on TRT than those who were not on TRT. A...
Here at Excelmale there are frequent posts discussing the pros and cons of statins, and one in particular several weeks ago where a position paper was cited where the assumption was that statins are not only a viable option but should be the first line of defense against heart disease. As I have...
A new study tracked men on TRT for five years and tracked cardiovascular events. It found about a 20% increased risk in men on TRT, mostly during the first two years. The abstract says:
"Using the UK Clinical Practice Research Datalink (CPRD), we formed a cohort of men aged 45 years or older...
This study is getting a lot of attention in the press today. It used "Mendelian randomization." Basically, some genetic variants cause men to have lower testosterone levels and the study compared the rates of heart disease between men with and without these genetic variations. The study used...
I was researching this topic and I found this study online. A few of you may know I questioned targeting higher free t3 during thyroid hormone replacement. Low free t3 and it’s effects on the cardiovascular system may have changed my mind. Theres accutually a good amount of research on this...
Testosterone to oestradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular events in men with severe atherosclerosis
Testosterone to estradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular events in men with severe...
Dr Lawson speaks about factors that can get in the way of effectiveness of testosterone replacement like thyroid dysfunction, insulin resistance, cardiovascular disease and exposure to toxins.Dr. Lawson is the founder and medical director of Proactive Wellness Centers, PLC (PWC) of Vienna...
Abstract from AUA2016.org
Low Serum Testosterone is Associated with Elevations in High-Sensitivity Cardiovascular Disease Biomarkers
Authors: Alexander W. Pastuszak*, Mark C. Lindgren, Samuel J. Ohlander, Amin Herati, Houston, TX, Joel Estis, Alameda, CA, Larry I. Lipshultz, Houston, TX...
Neutral associations of testosterone, dihydrotestosterone and estradiol with fatal and non-fatal cardiovascular events, and mortality in men aged 17-97 years
Chan, Y. X., Knuiman, M. W., Hung, J., Divitini, M. L., Beilby, J. P., Handelsman, D. J., Beilin, J., McQuillan, B. and Yeap, B. B...
Low serum free triiodothyronine levels are associated with the presence and severity of coronary artery disease in the euthyroid patients: an observational study.
Ertaş F, et al. Anadolu Kardiyol Derg. 2012.
Abstract
OBJECTIVE: The aim of this study is to investigate the relationship...
In a 2009 study, Dr. David Jenkins, of St. Michael's Hospital in Toronto, Canada, and colleagues found that a low-carbohydrate vegan diet - labeled as "Eco-Atkins" - was effective for weight loss. Now, new research from the team finds the diet may also reduce the risk of heart disease by 10%...
We all know that cholesterol is bad for us, right? At least that's the story we've all been told by conventional medicine and government health agencies for decades now. But what would you say if I told you that cholesterol doesn't cause heart disease and that it's actually essential to your...
For the current study, the researchers analyzed the results of 305 randomized controlled trials involving 339,274 individuals and found no statistically detectable differences between exercise and drug interventions for secondary prevention of heart disease and prevention of diabetes.
Among...
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