estetrol (e4); menopuase; hrt; safety/efficacy

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  1. madman

    Profile of estetrol (E4), a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause

    Hard to believe I missed posting this one been sitting on this paper since 2022! ABSTRACT Introduction Estrogens used in women’s healthcare have been associated with increased risks of venous thromboembolism (VTE) and breast cancer. Estetrol (E4), an estrogen produced by the human fetal...
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