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  1. G

    Increased sensitivity to estradiol after AI usage

    Hi, I have used arimidex multiple times throughout the years. Every time I tend to use this, when I come off the drug, I appear to be more sensitive to estrogen than I was previously i.e. development of gyno at natty levels, cessation of hair loss etc. Bloodwork is all normal, I have pretty...
  2. T

    Adding Arimidex to TRT protocol

    Hi. I have been on TRT for a few years now. My doctor has been telling me to take Arimidex to lower my estrogen but I have been trying everything to avoid it. My current protocol is 16mg Test Cyp Daily Subq 300IU HCG mon, wed, fri Blood level average over past few years with above protocol...
  3. D

    Stopped low dose AI, now experiencing ED?

    I've been on 40mg test cyp EOD for a number of months, and up until August 3rd (roughly 3 weeks ago) was taking 0.125mg compounded anastrozole every 6 days. This protocol seemed to work well and I felt pretty well balanced. I've recently moved into a new state which happens to be one of the...
  4. J

    Can a single dose of .25mg Arimidex crash my E2?

    I’m on HCG monotherapy. Mostly for fertility, but also loving the testosterone boost. My doctor decided to put me on 1000iu 3x per week. I started feeling sensitive (not painful) nipples. They aren’t sore, they’re just sensitive and they’re very hard often. No tissue growth. I also noticed my...
  5. M

    Anti AI crowd

    Wondering if anyone can clear up something for me about the anti AI crowd. You all know there are the guys that are not only against AI but that also say they don’t even check E2. They say they aren’t concerned about it and as long as your dose is right you don’t need to check it. But what...
  6. O

    DHEA + AI only protocol?

    Hello all, DHEA is bottom of range and I would like to bring it up. Problem is, it makes me lose wood at rather low doses from 10mg up. I am not on TRT and having weak adrenals. DHEA above 5mg does only work in combination with HC. My working theory is that DHEA increases estrogens and that's...
  7. S

    The best method of dialling in Aromasin dosage

    Dialling in your AI dosage can feel a bit like walking a tight rope, especially with Aromasin as crashing your E2 with it is more unforgiving than with Arimidex due to Aromasin's suicidal nature. A study Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane)...
  8. O

    Hcg and AI timing

    When is the best to inject HCG? Day before, day of test shot or day after? Also is it best take anastrozale day after test shot?
  9. B

    My solution for high estrogen after years of troubleshooting

    This is a bit wordy but I want to share what is working for me take get estrogen under control. I've been on TRT for over 6 years and estrogen has been my challenge. If you have battled this issue while on TRT, maybe this will work for you. And maybe I'm a slow learner and most of solving the...
  10. M

    High Estrogen Side Effects Help

    Hey guys Im in my first 6 months of starting TRT. My T dropped down pretty low and was the reasoning I got on TRT. I take 120mg of Test Cyp a week. Two injections along with HCG. My issues started with my Estrogen going up. I feel amazing mentally, physically and have amazing workouts currently...
  11. O

    How can I drop TT and DHT by a lot and E2 by a little?

    Hey guys, I got some alarming labs back a few weeks ago and am trying to make the right adjustments to my dosing protocol. This is a long post, so I hope it doesn't get ignored. I would really appreciate some help and I'm trying to give you any info that you might need without forcing you to...
  12. K

    How does Thyroid hormone effect Estrogen and Aromatase?

    I have searched for the answer endlessly and only got conflicting reports . Does Thyroid hormone ( T4,t3) reduce Estrogen or raise it ? What is their effects on the aromatase enzyme ? Thank you . All seems very confusing and I think the TRT/testosterone community could benefit from the correct...
  13. S

    Hot flashes are unlikely to be a symptom of increasing or increased E2, and more likely to be a symptom of decreases in E2 levels or low E2.

    After reading up a ton of literature on Estrogen effects on males, there's really a whole bunch of realisations about how extremely useful it is in male function and consequently how misunderstood and mishandled it is by men or TRT clinics. I'm glad Nelson seems to have a much better...
  14. K

    D-chiro-inositol raises testosterone significantly

    This study confirms that D-chiro-inositol raises Testosterone significantly and lowers E2 and Estrone : https://pubmed.ncbi.nlm.nih.gov/34078260/ Why is this not talked about anywhere ? Is there something wrong with the study ? Am I missing something ?
  15. T

    maybe AI isn't that bad?

    i started some other threads here, where HCG gave me awful mental symptoms, anxiety, insomnia etc, which happens about a week after starting it. i tried different doses, from 500iu 3x week, to 350iu 2x week - same results. for about a week I feel really good, libido is awesome (ok otherwise)...
  16. Pacman

    What is the timeline of how quick injectables and AIs affect us?

    For example, if I wanted to see if taking an AI would help with moodiness with my T shots, is it best to take an AI the same day, the day after, the day before? (Would it be better to use it as a "preventative" blocker?) Once you inject testosterone cypionate, do your T levels (and by...
  17. M

    Opinions on E2 management.

    On TRT for just over 4 years. Lately I've been part of a ******** group that also has a youtube channel: https://www.youtube.com/c/FoxPowerBasement They are all things TRT, however a very strong theme of the group is that NOBODY needs an AI. EVER. So for the past 6 months or so I have not...
  18. B

    High e2 and shbg

    Hey guys new member here! So I finished up my clomid a little over a week ago and got bloods done. I know it was too soon, but I felt really shitty. Estradiol-Ultrasensative 56 (<or29 pg/ml) SHBG 54 (10-50 Nmol/L) Total test 1526 (250-1100) Free test 241 (35-155) I feel pretty shitty...
  19. D

    Considering "micro dosing" AI?

    Weekly shot test cyp(I know), was recommended 48hrs post inject to take.5mg anastrazole. I found I felt much better taking anastrazole about the same time as shot. As it is preventative only, this made sense as the T spiked the ai would alongside. This does leave E perhaps unattended after a...
  20. Nelson Vergel

    Nelson Vergel Talks About Nandrolone, hCG, Hormone Ratios, AI’s, and More

  21. C

    Mixing Anastrozole with water?

    I know mixing the anastrozole with vodka for more accurate dosing. My question is, can I mix the AI with regular water? or with a lower-proof alcohol beverage(rice wine)? As I don't have a liquor store open around me. Any help is greatly appreciated, Thanks
  22. G

    Back to old regiment but T levels are through the roof

    Hi all, I posted a month ago about my trials an tribulations regarding my sweet spot was with high T 210mg/week and very low E < 5. only happy when estradiol is VERY low At that point I felt like conquering a small country over the weekend. Though my last nurse had approved it, my new nurse...
  23. F

    Does Anyone Feel Better on an AI?

    I know this topic has been beaten to death and with a little legwork, I am sure to find dozens of threads on this, so I apologize. But, like many here, I am still perplexed on why most forms of TRT I have tried cause side effects that outweigh the benefits. I have a ton of posts out there, but...
  24. M

    Anyone used/using calcium d glucarate for estrogen control?

    I've been reading a lot of good things lately about calcium d glucarate particularly in it's effectiveness of estrogen control. Just wondering if anyone on here has used it and can share their thoughts on it?
  25. S

    Empower .125 Anastrozole - Tablets?

    Been a while since I’ve gotten this product from them. Last time they were capsules. Just received some and they’re little round light green tablets with a split mark in the middle. That sound right? I can call in the morning but had planned on taking one tonight.
  26. S

    E2: what is "high" and "low"

    I see so many threads saying "if my E2 is too high or too low I get <x> symptom" but no numbers that show what that really is. My current routine, as an example, is 140 of T per week, injected once and 1mg of AI, once a week. It puts me at 980 at the low (day before shot) for T, and E2 of around...
  27. S

    Trt issues

    I started trt on Dec 30th 2020. I do 100mg of test weekly split into mon, wed, Fri injections. I take. .125mg of ai on mon, wed, Fri I'm wondering when I should take my ai. I can't get into the Dr's until March 1st so I'm asking you guys. I'm currently taking too much ai but wondering what days...
  28. C

    High E2 on latest labs

    Looking for some advice please. Current Protocol 100mg 2x weekly 500iu HCG 2x weekly No AI (Discontinued. It was 1mg 2x weekly and I felt it gave me mood swings) Latest Labs Total Testosterone >1500 E2 69pg/mL Notes: I'm not sure if the E2 test was sensitive or not, the labs don't show...
  29. Fernando Almaguer

    AI decreasing acne, drying it out at least some

    Ok, now I am not crazy.. lol but acne seems to lessen if I take some sort of AI. When I do not for a while I get very angry cystic acne on shoulders and lats and upper back. What gives here?
  30. U

    I found a TRT protocol that works

    So after trying injections for 2.5 years I went back to testosterone pellets. I'm one week in and my libido is already coming back strong. I started on pellets 6 years ago and stayed on them for 3 years and they always worked great. I stopped them because every now and then I'd have one that...
  31. Pacman

    Finding the right AI dosage

    So long story short, I have been for years without an AI. When I started taking them (1-2 a week @ 0.125 mg/pill) my sex drive got better. I had no idea I had an issue to begin with even with the blood tests with high estradiol due to the fact that I thought I felt fine (and my doctor said...
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