* Four main interrelated pathogenic factors, that act synergistically in a complex manner are involved in the development of acne lesions: 1. Increased sebum production due to androgen-driven sebaceous gland hyperplasia; 2. Hyperkeratinization of the follicular epithelium due to abnormal...
Management of Acne Vulgaris With Trifarotene (2023)
Jerry Tan, MD, Rajeev Chavda, MD, Hilary Baldwin, MD, and Brigitte Dreno, MD, PhD
Abstract
Topical retinoids have an essential role in the treatment of acne. Trifarotene, a topical retinoid selective for retinoic acid receptor (RAR) γ, is...
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